Ignet

Gene Information

Gene symbol: GJA8

Gene name: gap junction protein, alpha 8, 50kDa

HGNC ID: 4281

Synonyms: CX50

Related Genes

#	Gene Symbol	Number of hits
1	BCAP29	1 hits
2	CD1D	1 hits
3	CD200	1 hits
4	CD200R1	1 hits
5	CD8A	1 hits
6	CFDP1	1 hits
7	DEFB129	1 hits
8	FOLH1	1 hits
9	IFNG	1 hits
10	MSLN	1 hits
11	MUC1	1 hits
12	PLAUR	1 hits
13	TACSTD2	1 hits

Related Sentences

#	PMID	Sentence
1	3334743	Characterization of a recombinant vaccinia virus expressing human melanoma-associated antigen p97.
2	3334743	p97 is a cell surface glycoprotein expressed at high levels in most human melanomas but present only in trace amounts in normal adult tissues.
3	10669775	The urokinase receptor (uPAR) is a glycolipid anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes and cancer invasion.
4	11748189	In this study we demonstrate that the OprI lipoprotein (L-OprI) from Pseudomonas aeruginosa induces a long-term cellular (gamma interferon [IFN-gamma]) and humoral (immunoglobulin G2a) type 1 immune response against a truncated 32-kDa version (COOHgp63) of the 63-kDa major cell surface glycoprotein gp63.
5	12950675	The urokinase receptor (uPAR) is a glycolipid-anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes including cancer invasion.
6	14607868	A well-characterized subclass of these NKT cells expresses biased TCR and recognizes glycolipids such as alpha-galactoceramide, which is found naturally only in marine sponges and presented by the cell surface glycoprotein CD1d.
7	14607868	Observing high frequencies of CD4 and CD8 coreceptor expression in human CD56+ T cells, we examined the potential role of major histocompatibility complex (MHC) class II molecules in the activation of these cells.
8	14607868	Activation of mononuclear cells with bacterial superantigens presented by MHC class II molecules resulted in increased frequency of CD56+ T cells.
9	14607868	Primarily, CD4+ cells within the CD56+-T-cell population responded to the bacterial superantigens, and cytokine expression profiles were Th1-like.
10	14607868	Collectively, our data suggest that a significant number of CD56+ T cells recognize pathogen-associated ligands in association with MHC class II molecules.
11	19131115	Beta-defensin 129, T-cell surface glycoprotein CD8 and B-cell receptor-associated protein 29 were overexpressed in infected animals.
12	19131115	Lower expression levels of the immune response genes galectin-1, complement component C1qB and certain HLA class I and class II histocompatibility antigens and immunoglobulin chains were found in infected animals.
13	20635963	The prostate-specific membrane antigen is a cell-surface glycoprotein that is highly and specifically expressed on prostate epithelial cells and strongly upregulated in prostate cancer at all stages.
14	20662098	Tumor expression of CD200 inhibits IL-10 production by tumor-associated myeloid cells and prevents tumor immune evasion of CTL therapy.
15	20662098	CD200 is a cell-surface glycoprotein that functions through interaction with the CD200 receptor on myeloid lineage cells to regulate myeloid cell functions.
16	20662098	Tumor expression of CD200 significantly inhibited suppressive activity and IL-10 production by tumor-associated myeloid cells (TAMC), and as a result, more CTL accumulated in the tumor and exhibited a greater capacity to produce IFN-gamma in CD200-positive tumors than in CD200-negative tumors.
17	20662098	Thus, tumor expression of CD200 prevents tumor recurrence via inhibiting IL-10 production by TAMC.
18	22675251	The tumor-associated antigen GA733 is a cell-surface glycoprotein highly expressed in colorectal carcinomas.
19	23867519	In contrast, the poxvirus vaccine TG4010 produces an antigenic response to MUC1, a cell surface glycoprotein that reduces cell-cell interactions and thereby precludes contact inhibition.
20	24824231	Mesothelin is a cell-surface glycoprotein whose expression in normal human tissues is restricted to mesothelial cells.
21	25779534	Mesothelin (MSLN) is a cell surface glycoprotein, which is overexpressed in ovarian cancer tissues.