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Gene Information

Gene symbol: GNAS

Gene name: GNAS complex locus

HGNC ID: 4392

Synonyms: NESP55, NESP, GNASXL, GPSA, SCG6

Related Genes

#	Gene Symbol	Number of hits
1	ADCY10	1 hits
2	ADCY7	1 hits
3	GNAT1	1 hits

Related Sentences

#	PMID	Sentence
1	6350297	The protein toxin present in Bordetella pertussis vaccine blocks the inhibition of adenylate cyclase by prostaglandins and adenosine which may be secondary to ADP-ribosylation of an inhibitory guanine nucleotide-binding protein.
2	6350297	These data indicate that pertussis toxin selectively interferes with inhibition of cyclic AMP accumulation in rat adipocytes by adenosine, potentiates the increases in cyclic AMP due to catecholamines, increases the stimulatory effects of insulin on adipocyte metabolism, and interferes with alpha 1-catecholamine stimulation of phosphatidylinositol turnover.
3	8039872	The catalytic A subunit of cholera toxin (CT-A) is capable of ADP-ribosylating the guanine nucleotide-binding protein, which regulates cell adenylyl cyclase, leading to the life-threatening diarrhea of cholera.
4	8039872	Recombinant toxins (CT-1* and CT-2*), partially purified from culture supernatants of transformed JBK70, were shown to be inactive on mouse Y1 adrenal tumor cells and in an in vitro ADP-ribosyltransferase assay.
5	8039872	CT-1* and CT-2* reacted with polyclonal and monoclonal antibodies against both A and B subunits of CT.
6	19830419	The expression of pharmaceutically relevant proteins, including cell/viral surface proteins, membrane proteins, and guanine nucleotide-binding protein (G protein) coupled receptors, using silkworm larvae or cocoons has become very attractive.