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Gene Information

Gene symbol: GTF2A1

Gene name: general transcription factor IIA, 1, 19/37kDa

HGNC ID: 4646

Synonyms: TFIIA

Related Genes

# Gene Symbol Number of hits
1 ERBB2 1 hits
2 HSP90AA1 1 hits
3 HSP90B1 1 hits
4 HSPA1A 1 hits
5 HSPA5 1 hits

Related Sentences

# PMID Sentence
1 11566370 Glucose Regulated Protein (GRP78), a member of the 70 kDa heat-shock protein family was identified and characterised.
2 12000658 The recently cloned glucose regulated protein 78 (GRP78) of Leishmania donovani has been suggested as a new and promising Leishmania vaccine candidate.
3 16230366 Tumor-derived glucose-regulated protein 94 (GRP94/gp96) has shown great promise as a tumor vaccine.
4 20957756 Thus, a well-characterized HER-2/neu oncogene-driven mammary carcinogenesis model was analysed by various profiling strategies following "triplex" vaccination to identify new candidate targets for breast cancer immunoprevention. 2-DE-based proteomic profiling of preneoplastic and tumour lesions versus normal and aged mammary tissue demonstrated that tumour progression was associated with an up-regulation of molecular chaperones including glucose-regulated protein (GRP)78 and of proteins favouring cell motility, which was in line with the corresponding transcriptomic profiling data.
5 20957756 The distinct expression patterns for annexin A6 and GRP78 during tumour progression were further verified by western blot and/or immunoprecipitation.
6 21187087 Lipophosphoglycan 3 (LPG3), the Leishmania homologous with GRP94 (glucose regulated protein 94), a member of HSP90 family, is involved in assembly of LPG as the most abundant macromolecule on the surface of Leishmania promastigotes.
7 21621329 The HLHsp70 exhibits 90% amino acid identity to the putative Hsp70 of Ixodes scapularis, and 85% to Gallus gallus 78 kDa glucose-regulated protein precursor.
8 23725202 Tumour-derived chaperone-rich cell lysate (CRCL) when isolated from tumour tissue or when embedded with peptide antigens is a potent anti-cancer vaccine consisting of numerous chaperone/heat shock proteins, including the highly immunogenic Hsp70, Hsp90, glucose regulated protein 94, and calreticulin.