About

Home

Introduction

Statistics

Programs

Dignet

Gene

GenePair

BioSummarAI

Help & Docs

Documents

Help

FAQs

Links

Acknowledge

Disclaimer

Contact Us

Gene Information

Gene symbol: GTF2H2

Gene name: general transcription factor IIH, polypeptide 2, 44kDa

HGNC ID: 4656

Synonyms: BTF2, TFIIH, BTF2P44, T-BTF2P44, p44

Related Genes

#	Gene Symbol	Number of hits
1	EIF2AK2	1 hits
2	KHDRBS1	1 hits

Related Sentences

#	PMID	Sentence
1	21543505	NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.
2	21543505	Its NSs protein has previously been identified as a major virulence factor that suppresses host defense through three distinct mechanisms: it directly inhibits beta interferon (IFN-β) promoter activity, it promotes the degradation of double-stranded RNA-dependent protein kinase (PKR), and it suppresses host transcription by disrupting the assembly of the basal transcription factor TFIIH through sequestration of its p44 subunit.
3	21543505	Here, we report that in addition to PKR, NSs also promotes the degradation of the TFIIH subunit p62.
4	21543505	These data suggest that the RVFV NSs protein is able to interact with the TFIIH subunit p62 inside infected cells and promotes its degradation, which can occur directly in the nucleus.
5	21543505	NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.
6	21543505	Its NSs protein has previously been identified as a major virulence factor that suppresses host defense through three distinct mechanisms: it directly inhibits beta interferon (IFN-β) promoter activity, it promotes the degradation of double-stranded RNA-dependent protein kinase (PKR), and it suppresses host transcription by disrupting the assembly of the basal transcription factor TFIIH through sequestration of its p44 subunit.
7	21543505	Here, we report that in addition to PKR, NSs also promotes the degradation of the TFIIH subunit p62.
8	21543505	These data suggest that the RVFV NSs protein is able to interact with the TFIIH subunit p62 inside infected cells and promotes its degradation, which can occur directly in the nucleus.
9	21543505	NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.
10	21543505	Its NSs protein has previously been identified as a major virulence factor that suppresses host defense through three distinct mechanisms: it directly inhibits beta interferon (IFN-β) promoter activity, it promotes the degradation of double-stranded RNA-dependent protein kinase (PKR), and it suppresses host transcription by disrupting the assembly of the basal transcription factor TFIIH through sequestration of its p44 subunit.
11	21543505	Here, we report that in addition to PKR, NSs also promotes the degradation of the TFIIH subunit p62.
12	21543505	These data suggest that the RVFV NSs protein is able to interact with the TFIIH subunit p62 inside infected cells and promotes its degradation, which can occur directly in the nucleus.
13	21543505	NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.
14	21543505	Its NSs protein has previously been identified as a major virulence factor that suppresses host defense through three distinct mechanisms: it directly inhibits beta interferon (IFN-β) promoter activity, it promotes the degradation of double-stranded RNA-dependent protein kinase (PKR), and it suppresses host transcription by disrupting the assembly of the basal transcription factor TFIIH through sequestration of its p44 subunit.
15	21543505	Here, we report that in addition to PKR, NSs also promotes the degradation of the TFIIH subunit p62.
16	21543505	These data suggest that the RVFV NSs protein is able to interact with the TFIIH subunit p62 inside infected cells and promotes its degradation, which can occur directly in the nucleus.