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Gene Information
Gene symbol: HACL1
Gene name: 2-hydroxyacyl-CoA lyase 1
HGNC ID: 17856
Synonyms: 2-HPCL, PHYH2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | KRTAP11-1 | 1 hits |
| 2 | PRNP | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25542071 | Because of the discovery of 2-hydroxyacyl-CoA lyase (HACL1) as the first peroxisomal enzyme in mammals found to be dependent on thiamine pyrophosphate (TPP) and the ability of thiamine to bind with prion protein, these factors should improve our clinical approach to TD. |
| 2 | 25542071 | HACL1 has two important roles in alpha oxidation, the degradation of phytanic acid and shortening of 2-hydroxy long-chain fatty acids so that they can be degraded further by beta oxidation. |
| 3 | 25542071 | Because of the discovery of 2-hydroxyacyl-CoA lyase (HACL1) as the first peroxisomal enzyme in mammals found to be dependent on thiamine pyrophosphate (TPP) and the ability of thiamine to bind with prion protein, these factors should improve our clinical approach to TD. |
| 4 | 25542071 | HACL1 has two important roles in alpha oxidation, the degradation of phytanic acid and shortening of 2-hydroxy long-chain fatty acids so that they can be degraded further by beta oxidation. |