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Gene Information
Gene symbol: HBZ
Gene name: hemoglobin, zeta
HGNC ID: 4835
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | POLD4 | 1 hits |
| 4 | PRR6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20647569 | Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits. |
| 2 | 20647569 | We demonstrate that ablation of the HTLV-1 genes encoding p12, p30, or the HBZ protein, does not affect viral infectivity in rabbits and in this species, only the absence of HBZ is associated with a consistent reduction in virus levels. |
| 3 | 20647569 | Interestingly, we found that the p12 and the p30 mutants were also severely impaired in their ability to replicate in human dendritic cells. |
| 4 | 21677314 | HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated by the p30 and HBZ proteins. |
| 5 | 21677314 | The p13 protein directly binds Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transcriptional activity, suppresses viral expression. |
| 6 | 26063164 | HBZ-stimulated T cells killed HBZ peptide-pulsed T cells and CD4(+) T cells from HBZ transgenic (HBZ-Tg) mice. |
| 7 | 26063164 | Dendritic cells pulsed with this peptide could generate HBZ-specific CTLs from human CD8(+) T cells. |
| 8 | 26063164 | HBZ-stimulated T cells killed HBZ peptide-pulsed T cells and CD4(+) T cells from HBZ transgenic (HBZ-Tg) mice. |
| 9 | 26063164 | Dendritic cells pulsed with this peptide could generate HBZ-specific CTLs from human CD8(+) T cells. |