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Gene Information
Gene symbol: HDAC2
Gene name: histone deacetylase 2
HGNC ID: 4853
Synonyms: RPD3, YAF1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MYC | 1 hits |
| 2 | SRC | 1 hits |
| 3 | TFPI | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24489651 | Elevated TFPI1 in DOX resistant cells was active, as thrombin protein levels were coincidentally low. |
| 2 | 24489651 | We observed elevated HIF1α protein in DOX resistant cells, and in cells with forced expression of TFPI1, suggesting TFPI1 induces HIF1α. |
| 3 | 24489651 | TFPI1 also induced c-MYC, c-SRC, and HDAC2 protein, as well as DOX resistance in parental cells. |
| 4 | 24489651 | Growth of cells in 1% O2 induced elevated HIF1α, BCRP and MDR-1 protein, and these cells were resistant to DOX. |
| 5 | 24489651 | Our in vitro results were consistent with in vivo patient datasets, as tumors harboring increased BCRP and MDR-1 expression also had increased TFPI1 expression. |