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Gene Information
Gene symbol: HLA-DRB5
Gene name: major histocompatibility complex, class II, DR beta 5
HGNC ID: 4953
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HLA-A | 1 hits |
| 2 | HLA-C | 1 hits |
| 3 | HLA-DOB | 1 hits |
| 4 | HLA-DQA1 | 1 hits |
| 5 | HLA-DQB1 | 1 hits |
| 6 | HLA-DRA | 1 hits |
| 7 | HLA-DRB1 | 1 hits |
| 8 | HLA-DRB3 | 1 hits |
| 9 | HLA-DRB4 | 1 hits |
| 10 | HLA-G | 1 hits |
| 11 | HLA-H | 1 hits |
| 12 | MAGEA3 | 1 hits |
| 13 | MAGEC2 | 1 hits |
| 14 | S7 | 1 hits |
| 15 | SILV | 1 hits |
| 16 | TAP2 | 1 hits |
| 17 | TYR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15036912 | CM were synthesized that had defined lengths and contained aa corresponding to binding motifs of MHC class II molecules relevant in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), specifically HLA-DRB1*1501 and HLA-DRB5*0101, which are related to MS, and H2-IA(s) associated with EAE in SJL mice. |
| 2 | 15102786 | Human leukocyte antigen class II alleles influence levels of antibodies to the Plasmodium falciparum asexual-stage apical membrane antigen 1 but not to merozoite surface antigen 2 and merozoite surface protein 1. |
| 3 | 15102786 | This association for AMA1, combined with the previously reported association between HLA class II alleles and levels of antibodies to rhoptry-associated protein 1 (RAP1) and RAP2, indicates that HLA influences the levels of antibodies to three of the five vaccine candidate antigens that we have evaluated. |
| 4 | 17106278 | We found 10 class I alleles present in more than 10% of the population: HLA-A*02, HLA-A*11, HLA-A*24, HLA-B*13, HLA-B*15, HLA-B*40, HLA-Cw*03, HLA-Cw*07, HLA-Cw*01, and HLA-Cw*06. |
| 5 | 17106278 | Several class II alleles were found at high frequency (>or=10%): HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DRB1*0701, HLA-DRB1*1501, HLA-DRB1*0401, HLA-DRB1*0901, HLA-DRB1*1201, HLA-DQB1*0601, HLA-DQB1*0301, HLA-DQB1*0201, HLA-DQB1*0501, and HLA-DQB*0303. |
| 6 | 17106278 | The HLA-B*14 allele was only found in the HIV-1-seropositive group, and many 2-locus haplotypes were significantly overrepresented in this group: HLA-B*14/Cw*08, HLA-B*51/Cw*14, HLA-A*02/B*13, HLA-A*31/Cw*14, HLA-A*02/Cw*06, and the class II haplotype HLA-DRB1*1301/DQB1*0601. |
| 7 | 17106278 | Alleles significantly increased in the HIV-1-seronegative controls were HLA-B*44, HLA-Cw*04, and HLA-DRB1*1402. |
| 8 | 17106278 | Overrepresented 2-locus haplotypes in the control group were HLA-B*44/Cw*04, HLA-A*31/Cw*03, HLA-A*03/Cw*07, HLA-A*11/B*13, HLA-A*11/B*38, HLA-A*24/B*52, and HLA-A*11/Cw*01. |
| 9 | 21577140 | The immunostimulatory capacity of dendritic cells is improved by co-electroporation with mRNA encoding CD40 ligand, constitutively active toll-like receptor 4, and CD70 (TriMix-DC). |
| 10 | 21577140 | This pilot clinical trial evaluated the feasibility, safety, and immunogenicity of a therapeutic vaccination containing autologous TriMix-DC co-electroporated with mRNA encoding a human leukocyte antigen class II-targeting signal linked to 1 of 4 melanoma-associated antigens (MAGE-A3, MAGE-C2, tyrosinase, and gp100) in patients with advanced melanoma. |
| 11 | 24075919 | These SNPs were found to regulate the expression of a group of genes involved in antigen processing and presentation including HLA-A, HLA-C, HLA-G, HLA-H, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-DQA1, HLA-DQB1, HLA-DOB, and TAP-2. |