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Gene Information
Gene symbol: HMGA1
Gene name: high mobility group AT-hook 1
HGNC ID: 5010
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL11B | 1 hits |
| 2 | RN7SK | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24623795 | CTIP2 represses P-TEFb activity in a complex containing 7SK RNA and HEXIM1. |
| 2 | 24623795 | Here we show global synergy between CTIP2 and the 7SK-binding chromatin master-regulator HMGA1 in terms of P-TEFb-dependent endogenous and HIV-1 gene expression regulation. |
| 3 | 24623795 | While CTIP2 and HMGA1 concordingly repress the expression of cellular 7SK-dependent P-TEFb targets, the simultaneous knock-down of CTIP2 and HMGA1 also results in a boost in Tat-dependent and independent HIV-1 promoter activity. |
| 4 | 24623795 | Chromatin immunoprecipitation experiments reveal a significant loss of CTIP2/7SK/P-TEFb snRNP recruitment to cellular gene promoters and the HIV-1 promoter on HMGA1 knock-down. |
| 5 | 24623795 | Our findings not only provide insights into a recruiting mechanism for the inactive 7SK/P-TEFb snRNP, but may also contribute to a better understanding of viral latency. |