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Gene Information
Gene symbol: HYOU1
Gene name: hypoxia up-regulated 1
HGNC ID: 16931
Synonyms: ORP150, HSP12A, Grp170
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CALR | 1 hits |
| 2 | HSPA5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21339366 | However, contrary to other ER-resident heat shock proteins such as gp96, calreticulin, and ORP150, it is not clear whether tumor-derived BiP plays a role in inducing antitumor immunity. |
| 2 | 21339366 | In this study, we show that the tumor-derived secreted form of BiP is capable of inducing antitumor CD8(+) T cell responses. |
| 3 | 21339366 | We show that this secreted BiP is taken up by bone marrow-derived dendritic cells, and thereafter BiP-associated Ag peptide is cross-presented in association with MHC class I molecules, resulting in elicitation of an Ag-specific CD8(+) T cell response and antitumor effect. |