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Gene Information
Gene symbol: IER3
Gene name: immediate early response 3
HGNC ID: 5392
Synonyms: IEX-1, DIF-2, PRG1, IEX-1L
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL4 | 1 hits |
| 2 | CD83 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | CXCL2 | 1 hits |
| 5 | DEC1 | 1 hits |
| 6 | HLA-A | 1 hits |
| 7 | ICAM1 | 1 hits |
| 8 | IL1B | 1 hits |
| 9 | IL8 | 1 hits |
| 10 | IRF1 | 1 hits |
| 11 | NLRP3 | 1 hits |
| 12 | PDE4B | 1 hits |
| 13 | PTGS2 | 1 hits |
| 14 | TNF | 1 hits |
| 15 | TNFAIP3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15087407 | Three IEX-1-derived peptides at positions 47-56, 61-69, and 65-73, which were recognized by the 850B-CTLs, could induce CD8(+) peptide-specific CTL reaction to tumor cells from HLA-A33(+) gastric cancer patients and other epithelial cancer patients, but not from healthy donors, in an HLA class I-restricted manner. |
| 2 | 16697681 | As early as 1h postinfection, three genes, (IEX-1, IRF-1, DEC-1) all implicated in apoptosis pathways, were upregulated. |
| 3 | 17538120 | Upregulated genes included the immune regulatory molecules interleukin 1beta (IL-1beta), CIAS-1, tumor necrosis factor alpha, PDE4B, PTGS2, IL-8, CXCL2, CCL4, ICAM-1, CD83, GOS-2, IER3 (IEX-1), and TNFAIP3 (A20). |
| 4 | 17538120 | Plasma levels of IL-1beta and IL-8 were elevated during measles virus infection. |
| 5 | 17538120 | Downregulated genes mainly involved three gene ontology biological processes, transcription, signal transduction, and the immune response, and included IL-16 and cell surface receptors IL-4R, IL-6R, IL-7R, IL-27RA, CCR2, and CCR7. |