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Gene Information

Gene symbol: IGFBP7

Gene name: insulin-like growth factor binding protein 7

HGNC ID: 5476

Synonyms: MAC25, IGFBP-7, PSF, FSTL2

Related Genes

# Gene Symbol Number of hits
1 IGFALS 1 hits
2 IL10 1 hits
3 IL4 1 hits
4 INS 1 hits
5 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 20204282 Intratumoral injection of pEGFC1-IGFBP7 inhibits malignant melanoma growth in C57BL/6J mice by inducing apoptosis and down-regulating VEGF expression.
2 20204282 Recently, genome-wide RNA interference screening study revealed that loss of expression of insulin-like growth factor binding protein 7 (IGFBP-7) is a critical step in development of MM, and this secreted protein plays a central role in apoptosis of MM.
3 20204282 Intratumoral injection of pEGFC1-IGFBP7 inhibits malignant melanoma growth in C57BL/6J mice by inducing apoptosis and down-regulating VEGF expression.
4 20204282 Recently, genome-wide RNA interference screening study revealed that loss of expression of insulin-like growth factor binding protein 7 (IGFBP-7) is a critical step in development of MM, and this secreted protein plays a central role in apoptosis of MM.
5 23028860 Previously we have screened out Insulin-like Growth Factor Binding Protein 7 (IGFBP7) as a differentially expressed gene in post-implantation uterus versus pre-implantation uterus by suppressive subtractive hybridation.
6 23028860 After specific inhibition of IGFBP7, the T helper type 1 (Th1) cytokine IFNγ, was significantly elevated (p<0.05) and the Th2 cytokines IL-4 and IL-10, were reduced in uteri (p<0.05).
7 23028860 The expression of decidualization marker IGFBP1 and angiogenesis regulator VEGF were declined in uteri (p<0.05).
8 23028860 The expression of apoptosis-associated proteins, caspase3 and Bcl-2, were also declined (p<0.05).
9 23028860 Previously we have screened out Insulin-like Growth Factor Binding Protein 7 (IGFBP7) as a differentially expressed gene in post-implantation uterus versus pre-implantation uterus by suppressive subtractive hybridation.
10 23028860 After specific inhibition of IGFBP7, the T helper type 1 (Th1) cytokine IFNγ, was significantly elevated (p<0.05) and the Th2 cytokines IL-4 and IL-10, were reduced in uteri (p<0.05).
11 23028860 The expression of decidualization marker IGFBP1 and angiogenesis regulator VEGF were declined in uteri (p<0.05).
12 23028860 The expression of apoptosis-associated proteins, caspase3 and Bcl-2, were also declined (p<0.05).