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Gene Information

Gene symbol: IGHG1

Gene name: immunoglobulin heavy constant gamma 1 (G1m marker)

HGNC ID: 5525

Related Genes

#	Gene Symbol	Number of hits
1	IGHG2	1 hits
2	IGHG3	1 hits
3	IGHG4	1 hits
4	IL6	1 hits

Related Sentences

#	PMID	Sentence
1	12439618	These four genes were designated IGHG1, IGHG2, IGHG3 and IGHG4 on the basis of sequence similarities with the four human genes encoding the IgG1, IgG2, IgG3 and IgG4 subclasses and the three known rhesus macaque IGHG genes.
2	14678200	Although it is currently thought that rhesus macaques express three IgG subclasses, we identified four IGHG genes, which were designated IGHG1, IGHG2, IGHG3 and IGHG4 on the basis of sequence similarities with the four human genes encoding the IgG1, IgG2, IgG3 and IgG4 subclasses.
3	14678200	However, single amino acid substitutions were present in IGHG2 and IGHG4 genes, indicating the presence of IgG polymorphism possibly resulting in the expression of different allotypes.
4	25108787	Increased expression of IGHG1, IL6, IL1α, and IL1RN in bovine tick bite-site biopsies suggests that Th2 differentiation may be important for the local bovine response to A. americanum ticks.
5	25108787	The up-regulation of IL12 and IL23 in blood leukocytes from Lone Star tick-infested calves of all phenotypes suggests a possible systemic recruitment of memory T cells.
6	26311245	Most leukemic cells lacked the surface B cell markers CD19 and CD21.
7	26311245	IGHG1 or IGHG4/7 gene expression was consistent with surface protein expression, and secreted isotype and Ig spectratyping revealed one dominant monoclonal peak.
8	26311245	The mRNA expression of the B cell-associated developmental genes EBF1, PAX5, and CD19 was high compared to that of the plasma cell-associated marker CD38.