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Gene Information
Gene symbol: IGK
Gene name: immunoglobulin kappa locus
HGNC ID: 5715
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IGHV6-1 | 1 hits |
| 2 | IGL | 1 hits |
| 3 | IL15 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10918200 | IL-15 is an immunostimulatory cytokine with IL-2-like activities. |
| 2 | 10918200 | Significant IL-15 secretion was achieved only by the use of a modified cDNA encoding for an IL-15 pre-protein bearing the IgK light chain signal peptide. |
| 3 | 10918200 | TS/A IL-15 was restored in animals depleted of CD8(+) lymphocytes or of natural killer cells and partially in CD4(+)-depleted mice. |
| 4 | 10918200 | Cytolytic T lymphocyte (CTL) activity, specifically inhibited by anti-CD3 antibodies, was inducible in the splenocytes of TS/A IL-15-immunized animals by mixed lymphocyte/tumor culture (MLTC), and IFN-gamma was released in the supernatant of MLTC, mainly by CD8(+) cells. |
| 5 | 10918200 | Immunohistochemistry of the TS/A IL-15 tumor area revealed the presence of an inflammatory infiltrate with predominant natural killer, macrophage, and granulocyte components and expression of IFN-gamma as a distinctive secondary cytokine. |
| 6 | 25372838 | Losses involving IGK, IGL and IGH were always found, and gains along the length of chr13 and chr31 were often observed (>41%). |
| 7 | 25372838 | In these segments, MYC, LDHB, HSF1, KIT and PDGFRα are annotated. |