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Gene Information
Gene symbol: IGKV1-27
Gene name: immunoglobulin kappa variable 1-27
HGNC ID: 5735
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CR1 | 1 hits |
| 2 | CR2 | 1 hits |
| 3 | IL1A | 1 hits |
| 4 | IL1B | 1 hits |
| 5 | IL1R1 | 1 hits |
| 6 | IRAK3 | 1 hits |
| 7 | SIGIRR | 1 hits |
| 8 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10408376 | Targeting of influenza epitopes to murine CR1/CR2 using single-chain antibodies. |
| 2 | 10408376 | We have produced an scFv that recognizes murine complement receptors 1 and 2 (CR1/CR2) and genetically fused it with different numbers of influenza hemagglutinin peptides which contain both B and T cell epitopes. |
| 3 | 10408376 | The CR1/CR2 specific hybridoma 7G6 was used for RT-PCR to obtain the variable regions, which were then combined to create an scFv fragment. |
| 4 | 10408376 | The CR1/CR2 positive B lymphomas A20 and 2PK3 presented the peptide to an I-Ed restricted IP specific T cell hybridoma more efficiently when incubated with the IP(1)7G6 constructs as compared to the free peptide. |
| 5 | 22573738 | We demonstrated that direct exposure of porcine APCs to L. jensenii in the absence of inflammatory signals increased expression of interleukin-10 (IL-10) and transforming growth factor β in CD172a(+) APCs and caused them to display tolerogenic properties. |
| 6 | 22573738 | In addition, pretreatment of CD172a(+) APCs with L. jensenii resulted in differential modulation of the production of pro- and anti-inflammatory cytokines in response to TLR4 activation. |
| 7 | 22573738 | The immunomodulatory effect of strain TL2937 was not related to a downregulation of TLR4 but was related to an upregulation of the expression of three negative regulators of TLRs: single immunoglobulin IL-1-related receptor (SIGIRR), A20, and interleukin-1 receptor-associated kinase M (IRAK-M). |
| 8 | 22573738 | Our results also indicated that TLR2 has an important role in the anti-inflammatory activity of L. jensenii TL2937, since anti-TLR2 antibodies blocked the upregulation of SIGIRR and IRAK-M in CD172a(+) APCs and the production of IL-10 in response to TLR4 activation. |