# |
PMID |
Sentence |
1 |
24862931
|
Genetic analysis of selected Fabs indicated that the IGHV and IGLV differ from the germ-line sequence.
|
2 |
24862931
|
At the level of nucleotide sequences, the IGHV and IGLV domains were found to share 74-92% and 90-96% homology with sequences encoded by the corresponding human germ-line genes respectively.
|
3 |
24862931
|
IGHJ3 and IGHJ4 genes are predominantly used in RV-Fab.
|
4 |
24862931
|
The IGLV domains are dominated by IGKV1, IGLV1 and IGLV3 genes.
|
5 |
24862931
|
Numerous somatic hypermutations in the RV-specific IGHV are detected, but only limited amino acid replacement in most of the RV-specific IGLV particularly in those encoded by J proximal IGLV or IGKV genes are found.
|
6 |
24862931
|
Genetic analysis of selected Fabs indicated that the IGHV and IGLV differ from the germ-line sequence.
|
7 |
24862931
|
At the level of nucleotide sequences, the IGHV and IGLV domains were found to share 74-92% and 90-96% homology with sequences encoded by the corresponding human germ-line genes respectively.
|
8 |
24862931
|
IGHJ3 and IGHJ4 genes are predominantly used in RV-Fab.
|
9 |
24862931
|
The IGLV domains are dominated by IGKV1, IGLV1 and IGLV3 genes.
|
10 |
24862931
|
Numerous somatic hypermutations in the RV-specific IGHV are detected, but only limited amino acid replacement in most of the RV-specific IGLV particularly in those encoded by J proximal IGLV or IGKV genes are found.
|
11 |
24862931
|
Genetic analysis of selected Fabs indicated that the IGHV and IGLV differ from the germ-line sequence.
|
12 |
24862931
|
At the level of nucleotide sequences, the IGHV and IGLV domains were found to share 74-92% and 90-96% homology with sequences encoded by the corresponding human germ-line genes respectively.
|
13 |
24862931
|
IGHJ3 and IGHJ4 genes are predominantly used in RV-Fab.
|
14 |
24862931
|
The IGLV domains are dominated by IGKV1, IGLV1 and IGLV3 genes.
|
15 |
24862931
|
Numerous somatic hypermutations in the RV-specific IGHV are detected, but only limited amino acid replacement in most of the RV-specific IGLV particularly in those encoded by J proximal IGLV or IGKV genes are found.
|
16 |
24862931
|
Genetic analysis of selected Fabs indicated that the IGHV and IGLV differ from the germ-line sequence.
|
17 |
24862931
|
At the level of nucleotide sequences, the IGHV and IGLV domains were found to share 74-92% and 90-96% homology with sequences encoded by the corresponding human germ-line genes respectively.
|
18 |
24862931
|
IGHJ3 and IGHJ4 genes are predominantly used in RV-Fab.
|
19 |
24862931
|
The IGLV domains are dominated by IGKV1, IGLV1 and IGLV3 genes.
|
20 |
24862931
|
Numerous somatic hypermutations in the RV-specific IGHV are detected, but only limited amino acid replacement in most of the RV-specific IGLV particularly in those encoded by J proximal IGLV or IGKV genes are found.
|
21 |
24965774
|
Sequencing of IGHV, IGLV, IGKV, and BCL6 genes from these D-specific B cell clones demonstrated that both CD27(-)IgM(+) and CD27(+)IgM(+) B cells harbored somatic mutations, documenting their Ag-selected nature.
|
22 |
25996084
|
A sorting strategy was developed using a panel of molecular markers (CD3, CD19, CD20, surface IgG, intracellular IgG, CD27, Ki67 and CD38) to identify the kinetics of B cell response after vaccination.
|
23 |
25996084
|
Sequence analysis revealed that diverse IGHV subgroups (for VH) and IGKV and IGLV subgroups (for VL) were represented in the cloned antibodies.
|