Ignet

Gene Information

Gene symbol: IKZF2

Gene name: IKAROS family zinc finger 2 (Helios)

HGNC ID: 13177

Synonyms: Helios

Related Genes

#	Gene Symbol	Number of hits
1	CD4	1 hits
2	CD8A	1 hits
3	CELIAC3	1 hits
4	CRLF2	1 hits
5	CTLA4	1 hits
6	FOXP3	1 hits
7	PDCD1	1 hits
8	PECAM1	1 hits
9	TSLP	1 hits
10	VSIG4	1 hits

Related Sentences

#	PMID	Sentence
1	18432878	A general procedure is included for cloning of cytokine genes, for example, murine GM-CSF, in A20 lymphoma cells.
2	18432878	Support protocols are presented for chemically conjugating intact Ig protein with KLH to produce a prototype protein vaccine and using the Helios Gene Gun System to immunize mice with recombinant DNA tumor vaccines.
3	21677778	Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.
4	23104354	Biolistic immunization with the Helios gene gun has proven to be potent in the induction of antigen-specific CD4(+) and CD8(+) T cells.
5	23515135	TSLP-TSLPR (TSLP receptor) interactions also promoted the expansion of colonic Helios(-)Foxp3(+) regulatory T cells, necessary for the control of inappropriate Th17 responses following ASF bacterial colonization.
6	23748671	Flow-sorted CD3(+)CD4(+)CD25(+)CD127(low) Tregs were stimulated with anti-CD3/anti-CD28 coated beads and cultured in the presence of IL-2.
7	23748671	The expanded Tregs expressed high levels of FOXP3, CTLA4 and HELIOS compared to conventional T cells and were shown to be highly suppressive.
8	25825451	Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells.
9	25825451	We also show that DN T cells derived from self-reactive CD8 cells express the inhibitory molecules PD-1 and Helios.
10	25825451	Collectively, our data suggest that a subset of DN T cells, identified by the expression of PD-1 and Helios, represent self-reactive cells.
11	25825451	Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells.
12	25825451	We also show that DN T cells derived from self-reactive CD8 cells express the inhibitory molecules PD-1 and Helios.
13	25825451	Collectively, our data suggest that a subset of DN T cells, identified by the expression of PD-1 and Helios, represent self-reactive cells.
14	25825451	Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells.
15	25825451	We also show that DN T cells derived from self-reactive CD8 cells express the inhibitory molecules PD-1 and Helios.
16	25825451	Collectively, our data suggest that a subset of DN T cells, identified by the expression of PD-1 and Helios, represent self-reactive cells.
17	26324156	Helios(+)Foxp3(+) and Helios(-)Foxp3(+) Treg cells were unaffected with age.
18	26324156	Recent thymic emigrants, based on CD31 expression, were decreased among the Helios(+)Foxp3(+), but not the Helios(-)Foxp3(+) cell populations.
19	26324156	Helios(+)Foxp3(+) and Helios(-)Foxp3(+) Treg cells were unaffected with age.
20	26324156	Recent thymic emigrants, based on CD31 expression, were decreased among the Helios(+)Foxp3(+), but not the Helios(-)Foxp3(+) cell populations.