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Gene Information
Gene symbol: IL17RA
Gene name: interleukin 17 receptor A
HGNC ID: 5985
Synonyms: hIL-17R, IL-17RA, CDw217, CD217
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL10 | 1 hits |
| 2 | IL17A | 1 hits |
| 3 | IL17F | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23529615 | The presence of IL-10 appeared to restrain the expression of IL-17, since high levels of splenic IL-17 were observed after intradermal LVS infection only in IL-10(-/-) mice. |
| 2 | 23529615 | However, neutralization of IL-10 activity in IL-17R(-/-) mice failed to provide protection. |
| 3 | 23529615 | Thus, IL-10 suppresses a protective IL-17 response that is necessary for resistance to cutaneous LVS infection. |
| 4 | 24600029 | Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. |
| 5 | 24600029 | Functional studies with mice deficient of IL-17R, IL-17A, and IL-17F further revealed that IL-17 signaling was critical for priming T cell responses in viral hepatitis. |
| 6 | 24600029 | IL-17A repressed IL-17F secretion in vitro and in vivo; IL-17F(+) intrahepatic cells expanded more vigorously in IL-17A knockout animals, permitting efficient Ag presentation and T cell function. |
| 7 | 24600029 | However, IL-17F neither inhibited IL-17A in vitro nor regulated its secretion in vivo. |