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Gene Information
Gene symbol: INPP5D
Gene name: inositol polyphosphate-5-phosphatase, 145kDa
HGNC ID: 6079
Synonyms: SHIP, hp51CN
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD19 | 1 hits |
| 2 | CD22 | 1 hits |
| 3 | CR2 | 1 hits |
| 4 | MIRN155 | 1 hits |
| 5 | MYD88 | 1 hits |
| 6 | PTPN6 | 1 hits |
| 7 | PTPRC | 1 hits |
| 8 | SLURP1 | 1 hits |
| 9 | SYNJ1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9597145 | Recent findings in B lymphocytes have clearly illustrated that these external inputs affect the magnitude and duration of the intracellular calcium response, which in turn contributes to differential triggering of the transcriptional regulators NF kappa B, JNK, NFAT, and ERK. |
| 2 | 9597145 | The regulation of calcium responses involves a network of tyrosine kinases (e.g. lyn, syk), tyrosine or lipid phosphatases (CD45, SHP-1, SHIP), and accessory molecules (CD21/CD19, CD22, FcR gamma 2b). |
| 3 | 21339365 | MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4. |
| 4 | 21339365 | Moreover, when tested in TRIF-intact/MyD88-deficient DCs, synthetic MLA of the Escherichia coli chemotype (sMLA) showed the same activity as its diphosphoryl, inflammatory counterpart (synthetic diphosphoryl lipid A), indicating that TRIF-mediated signaling is fully induced by sMLA. |
| 5 | 25295729 | Additional studies demonstrated that miR-155 acted by translational repression to downregulate the TLR adapter protein MyD88 and the inositol 5'-phosphatase SHIP-1 in MDMs infected with F. tularensis LVS or the fully virulent strain Schu S4. |
| 6 | 25295729 | Dynamic modulation of MyD88 and SHIP-1 was confirmed using specific pre-miRs and anti-miRs to increase and decrease miR-155 levels, respectively. |
| 7 | 25295729 | Additional studies demonstrated that miR-155 acted by translational repression to downregulate the TLR adapter protein MyD88 and the inositol 5'-phosphatase SHIP-1 in MDMs infected with F. tularensis LVS or the fully virulent strain Schu S4. |
| 8 | 25295729 | Dynamic modulation of MyD88 and SHIP-1 was confirmed using specific pre-miRs and anti-miRs to increase and decrease miR-155 levels, respectively. |