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Gene Information
Gene symbol: IPO9
Gene name: importin 9
HGNC ID: 19425
Synonyms: Imp9, FLJ10402
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
23734163
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Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage.
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2 |
23734163
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Extrachromosomal histone H2B acts as a cytosolic sensor to detect double-stranded DNA (dsDNA) fragments derived from infectious agents or damaged cells to activate innate and acquired immune responses in various cell types.
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3 |
23734163
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It also physically interacts with interferon (IFN)-β promoter stimulator 1 (IPS-1), an essential adaptor molecule that activates innate immunity, through COOH-terminal importin 9-related adaptor organizing histone H2B and IPS-1 (CIAO), resulting in a distinct signaling complex that induces dsDNA-induced type I IFN production.
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