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Gene Information

Gene symbol: IVNS1ABP

Gene name: influenza virus NS1A binding protein

HGNC ID: 16951

Synonyms: NS1-BP, HSPC068, NS-1, KIAA0850, ND1, KLHL39

Related Genes

# Gene Symbol Number of hits
1 AAVS1 1 hits
2 CD4 1 hits
3 CD8A 1 hits
4 FCGR1A 1 hits
5 KRAS 1 hits
6 RAF1 1 hits

Related Sentences

# PMID Sentence
1 17582005 Antibody recognition of cell surface-associated NS1 triggers Fc-gamma receptor-mediated phagocytosis and clearance of West Nile Virus-infected cells.
2 17582005 Previous studies have suggested that monoclonal antibodies (MAbs) to flavivirus nonstructural protein-1 (NS-1) protect against infection in mice through an Fc-gamma receptor-dependent pathway.
3 17582005 Our results suggest that only MAbs that recognize cell surface-associated NS1 trigger Fc-gamma receptor I- and/or IV-mediated phagocytosis and clearance of WNV-infected cells.
4 18160141 In contrast, the half-lives for adeno-associated virus (AAV) preparations were similar (63 ns(-1) 8-MOP vs. 67 ns(-1) riboflavin).
5 21881953 Dengue virus-specific CD4+ and CD8+ T lymphocytes target NS1, NS3 and NS5 in infected Indian rhesus macaques.
6 21881953 DENV-specific CD4+ and CD8+ T lymphocytes targeted nonstructural (NS) 1, NS3 and NS5 proteins after resolution of peak viremia.
7 21881953 DENV-specific CD4+ cells expressed interferon-gamma (IFN-γ) along with tumor necrosis factor-alpha (TNF-α), interleukin-2 (IL-2), and macrophage inflammatory protein-1 beta (MIP-1β).
8 21881953 In comparison, DENV-specific CD8+ cells expressed IFN-γ in addition to MIP-1β and TNF-α and were positive for the degranulation marker CD107a.
9 21881953 Interestingly, a fraction of the DENV-specific CD4+ cells also stained for CD107a, suggesting that they might be cytotoxic.