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Gene Information

Gene symbol: JARID1B

Gene name: jumonji, AT rich interactive domain 1B

HGNC ID: 18039

Related Genes

# Gene Symbol Number of hits
1 CD44 1 hits
2 CLOCK 1 hits
3 CSAG1 1 hits
4 CTAGE1 1 hits
5 CTDSP1 1 hits
6 DDX43 1 hits
7 DDX53 1 hits
8 DLK1 1 hits
9 DNAH17 1 hits
10 PASD1 1 hits
11 PIAS2 1 hits
12 PRAME 1 hits
13 PROM1 1 hits
14 SPA17 1 hits

Related Sentences

# PMID Sentence
1 14639620 Patients had been treated within 2 clinical trials with autologous tumor cells gene-modified for IL-7 or IL-12.
2 14639620 Besides 2 known cancer-germline genes (SCP-1 and PLU-1), the other isolated antigens were expressed in a non-tumor-specific fashion as analyzed by virtual Northern blot or RT-PCR.
3 14639620 The properties of homologues to several of the identified tumor-antigens, especially PLU-1, SCP-1, DNEL2, CLOCK, and PIASx-alpha, suggest further investigation of their possible function in malignant melanoma.
4 14639620 Patients had been treated within 2 clinical trials with autologous tumor cells gene-modified for IL-7 or IL-12.
5 14639620 Besides 2 known cancer-germline genes (SCP-1 and PLU-1), the other isolated antigens were expressed in a non-tumor-specific fashion as analyzed by virtual Northern blot or RT-PCR.
6 14639620 The properties of homologues to several of the identified tumor-antigens, especially PLU-1, SCP-1, DNEL2, CLOCK, and PIASx-alpha, suggest further investigation of their possible function in malignant melanoma.
7 20726502 The broadest mRNA expression profiles were observed for the following eight CT genes: Sp17 (25/25), PRAME (25/25), CSAGE (24/25), PASD1 (22/25), CAGE/DDX53 (19/25), CTAGE1 (19/25), HAGE/DDX43 (16/25) and PLU-1/JARID1B (15/25).
8 23896726 Here we identified the NOTCH antagonist delta-like 1 homologue (DLK1) as a vascular pericyte-associated antigen expressed in renal cell carcinomas (RCC), but not in normal kidney tissues in mice and humans.
9 23896726 After therapeutic vaccination, tumors displayed increased prevalence of activated VCAM1(+)CD31(+) vascular endothelial cells (VECs) and CXCL10, a type-1 T cell recruiting chemokine, in concert with increased levels of type-1 CD8(+) tumor-infiltrating lymphocytes (TIL).
10 23896726 Vaccination against DLK1 also yielded (i) dramatic reductions in Jarid1B(+), CD133(+), and CD44(+) (hypoxia-responsive) stromal cell populations, (ii) enhanced tumor cell apoptosis, and (iii) increased NOTCH signaling in the TME.