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Gene Information
Gene symbol: KIR2DS2
Gene name: killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
HGNC ID: 6334
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HLA-A | 1 hits |
| 2 | KIR2DL1 | 1 hits |
| 3 | KIR2DL2 | 1 hits |
| 4 | KIR2DL3 | 1 hits |
| 5 | KIR2DL5A | 1 hits |
| 6 | KIR2DS1 | 1 hits |
| 7 | KIR2DS3 | 1 hits |
| 8 | KIR2DS4 | 1 hits |
| 9 | KIR2DS5 | 1 hits |
| 10 | KIR3DL1 | 1 hits |
| 11 | KLRB1 | 1 hits |
| 12 | KLRC2 | 1 hits |
| 13 | KLRK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15557759 | These altered HLA class I phenotypes and non-ubiquitous expression of NK receptor ligands constitute the major tumor escape mechanism facing tumor-specific CTL and/or NK cell mediated responses. |
| 2 | 17462078 | Differential induction of CD94 and NKG2 in CD4 helper T cells. |
| 3 | 17462078 | In this study we investigated CD94 and NKG2 gene expression in memory CD4 T-cell clones established from the spleens of C57BL/10 (H-2(b)) and BALB/c (H-2(d)) mice infected with influenza A virus (H3N2). |
| 4 | 17462078 | CD94 and NKG2A/C/E proteins form heterodimeric membrane receptors that are involved in virus recognition. |
| 5 | 17462078 | CD94 and NKG2 expression have been well characterized in natural killer (NK) and cytotoxic T cells. |
| 6 | 17462078 | Despite CD94 being potentially an important marker for Th1 cells involved in virus infection, however, there has been little investigation of its expression or function in the CD4 T-cell lineage and no studies have looked at in-vivo-generated Th cells or memory cells. |
| 7 | 17462078 | We show in this study that in-vivo-generated CD4 Th1 cells, but not Th2 cells, exhibited full-length CD94 and NKG2A gene expression following activation with viral peptide. |
| 8 | 17462078 | Another member of the NK receptor family, NKG2D, but not NKG2C or E, was also differentially expressed in Th1 cells. |
| 9 | 17462078 | We show here that CD94 and NKG2A may exist as multiple isoforms with the potential to distinguish helper T-cell subsets. |
| 10 | 23594113 | Our data showed that the inhibitory gene frequency of genes KIR2DL1, KIR2DL3, KIR3DL1, KIR2DL5 and KIR2DL2 was 0.930, 0.889, 0.789, 0.206 and 0.095, respectively, and the activating gene frequency of KIR2DS4, KIR3DS1, KIR2DS1, KIR2DS5, KIR2DS2 and KIR2DS3 was 0.795, 0.218, 0.196, 0.165, 0.095 and 0.087, respectively. |
| 11 | 24130485 | This recognition depends on the detection of microbial compounds presented by the evolutionarily conserved major-histocompatibility-complex (MHC) class I molecule, MR1. |
| 12 | 24130485 | The NK receptor, CD161, highly expressed by MAIT cells, modulated the cytokine but not the cytotoxic response triggered by bacteria infected cells. |