Ignet

Gene Information

Gene symbol: LIF

Gene name: leukemia inhibitory factor

HGNC ID: 6596

Synonyms: CDF, DIA, HILDA

Related Genes

#	Gene Symbol	Number of hits
1	CNTF	1 hits
2	CSF2	1 hits
3	FSCN1	1 hits
4	HPD	1 hits
5	IGF1	1 hits
6	IL11	1 hits
7	IL4	1 hits
8	IL6	1 hits
9	IL7	1 hits
10	LBR	1 hits
11	LIFR	1 hits
12	NUDT6	1 hits
13	TNF	1 hits

Related Sentences

#	PMID	Sentence
1	133010	B-cell deficiencies such as hypogammaglobulinaemia, have normal PPD and PHA induced LIF production, whilst some patients with ataxia-telangiectasia have defective PPD LIF activity, their PHA LIF activity being only minimally depressed.
2	11916244	Brain tumor-bearing mice were treated with cytokine (IL -4, IL-6, IL-7, GM-CSF, TNF-alpha, LIF, LT) producing vaccines made by in vitro transduction of GI261 cells with the corresponding adenoviral vectors.
3	11916244	Vaccines producing either IL-4 or GM-CSF cured 20-40% of mice.
4	11916244	Brain tumors were heavily infiltrated by CD4+ lymphocytes after treatment with IL-4- or GM-CSF-secreting cells.
5	11916244	GM-CSF vaccination induced moderate CD8+ infiltration, as well.
6	11916244	Depleting either CD4+ or CD8+ lymphocyte subsets abolished the anticancer effect of GM-CSF-expressing cells.
7	11916244	Strong synergism was observed by combining cytokine vaccination (GM-CSF, IL-4, IL-12) with local tumor irradiation: about 80-100% of the glioma-bearing mice was cured.
8	22139866	Leukemia inhibitory factor (LIF), a member of interleukin-6 family, is required for embryo development and successful blastocyst implantation in several mammalian species.
9	22139866	Three sequences from LIF and two sequences from LIF-receptor (LIF-R) that span the regions involved in ligand-receptor binding were delineated, and peptides were synthesized based upon these sequences.
10	22139866	The data indicate that LIF/LIF-R is an excellent target for the development of a birth control vaccine.
11	22139866	This is the first study, to our knowledge, that examined LIF/LIF-R as a target for immunocontraception.
12	22139866	The findings of this study can be easily translated to humans since LIF/LIF-R is also important for implantation and pregnancy in women.
13	22139866	Leukemia inhibitory factor (LIF), a member of interleukin-6 family, is required for embryo development and successful blastocyst implantation in several mammalian species.
14	22139866	Three sequences from LIF and two sequences from LIF-receptor (LIF-R) that span the regions involved in ligand-receptor binding were delineated, and peptides were synthesized based upon these sequences.
15	22139866	The data indicate that LIF/LIF-R is an excellent target for the development of a birth control vaccine.
16	22139866	This is the first study, to our knowledge, that examined LIF/LIF-R as a target for immunocontraception.
17	22139866	The findings of this study can be easily translated to humans since LIF/LIF-R is also important for implantation and pregnancy in women.
18	22139866	Leukemia inhibitory factor (LIF), a member of interleukin-6 family, is required for embryo development and successful blastocyst implantation in several mammalian species.
19	22139866	Three sequences from LIF and two sequences from LIF-receptor (LIF-R) that span the regions involved in ligand-receptor binding were delineated, and peptides were synthesized based upon these sequences.
20	22139866	The data indicate that LIF/LIF-R is an excellent target for the development of a birth control vaccine.
21	22139866	This is the first study, to our knowledge, that examined LIF/LIF-R as a target for immunocontraception.
22	22139866	The findings of this study can be easily translated to humans since LIF/LIF-R is also important for implantation and pregnancy in women.
23	22139866	Leukemia inhibitory factor (LIF), a member of interleukin-6 family, is required for embryo development and successful blastocyst implantation in several mammalian species.
24	22139866	Three sequences from LIF and two sequences from LIF-receptor (LIF-R) that span the regions involved in ligand-receptor binding were delineated, and peptides were synthesized based upon these sequences.
25	22139866	The data indicate that LIF/LIF-R is an excellent target for the development of a birth control vaccine.
26	22139866	This is the first study, to our knowledge, that examined LIF/LIF-R as a target for immunocontraception.
27	22139866	The findings of this study can be easily translated to humans since LIF/LIF-R is also important for implantation and pregnancy in women.
28	22139866	Leukemia inhibitory factor (LIF), a member of interleukin-6 family, is required for embryo development and successful blastocyst implantation in several mammalian species.
29	22139866	Three sequences from LIF and two sequences from LIF-receptor (LIF-R) that span the regions involved in ligand-receptor binding were delineated, and peptides were synthesized based upon these sequences.
30	22139866	The data indicate that LIF/LIF-R is an excellent target for the development of a birth control vaccine.
31	22139866	This is the first study, to our knowledge, that examined LIF/LIF-R as a target for immunocontraception.
32	22139866	The findings of this study can be easily translated to humans since LIF/LIF-R is also important for implantation and pregnancy in women.
33	25553348	Then the cells were cultured on inactivated mouse SNL feeder cells in the presence of LIF, IGF-1, bFGF, CNTF, OSM, SCF, Il-6, and Il-11 growth factors.
34	25553348	Furthermore, the expression of pluripotency (cPouV, Sox2, and Nanog) and cell lineage specific (Cvh, Brachyury, and Gata6) gene markers was evaluated at the level of mRNA using quantitative RT-PCR.
35	25553348	The stemness of embryonic cells has been approved by the activity of the alkaline phosphatase, presence of the SSEA-4, and TRA-1-60 protein, and expression of the molecular marker (cPouV, Nanog, and Sox-2) genes.