- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: LILRB4
Gene name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
HGNC ID: 6608
Synonyms: LIR-5, ILT3, HM18, LIR5, CD85k
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD1D | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | CXCL2 | 1 hits |
| 5 | DBH | 1 hits |
| 6 | FAS | 1 hits |
| 7 | FASLG | 1 hits |
| 8 | FCGR2C | 1 hits |
| 9 | FTH1 | 1 hits |
| 10 | HLA-G | 1 hits |
| 11 | IL10 | 1 hits |
| 12 | LILRB2 | 1 hits |
| 13 | NFKB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15061571 | Specific strategies for autoimmune diseases might include interference with cross-priming events that activate autoreactive T cells and genetic engineering to introduce molecules that have immunosuppressive functions, such as IL-10, TGF3, Fas ligand, ILT3, and ILT4. |
| 2 | 18848854 | Using the human leukocyte antigen-A0201 restricted immunodominant cytomegalovirus epitope pp65-NLVPMVATV for pulsing either mature/immunogenic or ILT3(high)ILT4(high) tolerogenic dendritic cells (DC), we generated cytotoxic and suppressor CD8(+) T-cell lines, respectively. |
| 3 | 19275918 | They are traditionally viewed as the immunologic centerpiece that is able to prime CD4(+) helper and CD8(+) cytotoxic T-cell effector populations. |
| 4 | 19275918 | DC overexpressing ILT3 display lower phosphorylation levels of NF-kappaB and fail to stimulate the full program of Th proliferation and maturation eliciting instead the differentiation of CD8(+) T(S) and CD4(+) Treg. |
| 5 | 19524004 | DC-expressed ILT3 and ILT4 are stimulated by their cognate ligands such as major histocompatibility complex class I (MHC-I), HLA-G, and CD1d, and this stimulation is a prerequisite for DC tolerization. |
| 6 | 21108342 | The up-regulated genes include genes encoding immunoglobulin, histocompatibility 2 (K region), and several complement component genes, while the down-regulated genes include the TAP1 (transporters associated with antigen processing gene-1), interferon induced gene (Ifi203), chemokine (C-X-C) ligands and leukocyte-immunoglobulin-like genes, Lck-interacting transmembrane adaptor genes and histocompatibility 2 (Q region and T region). |
| 7 | 21108342 | The immune-related six genes up-regulated with immunogenic complex treatment were Fcgr2b, Cxcl2, Fth1, Clec4n, Lilrb4, and Dbh, with Fcgr2b (Fc gamma receptor IIB) being the highest up-regulated gene. |