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Gene Information
Gene symbol: LIMS1
Gene name: LIM and senescent cell antigen-like domains 1
HGNC ID: 6616
Synonyms: PINCH, PINCH1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HAVCR2 | 1 hits |
| 2 | ITK | 1 hits |
| 3 | LGALS9 | 1 hits |
| 4 | MUC1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25279150 | Induction of HLA-A*33-restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH. |
| 2 | 25279150 | Galectin 9, a ligand of T cell immunoglobulin and mucin domain 3 (TIM-3), and PINCH, an epithelial-to-mesenchymal transition (EMT)-promoting molecule, are expressed at much higher levels in cancerous lesions of clear cell type renal cell carcinoma (RCC) compared to normal renal tissues, and their expression levels are extremely low in normal tissues, except for galectin 9 in the spleen. |
| 3 | 25279150 | Galectin 9- and PINCH-derived peptides have previously been shown to induce human leukocyte antigen (HLA)-A*2402-restricted and HLA-A*0201-restricted cytotoxic lymphocytes (CTLs) with specific and highly cytotoxic activities toward RCC cells. |