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Gene Information

Gene symbol: LRRN2

Gene name: leucine rich repeat neuronal 2

HGNC ID: 16914

Synonyms: GAC1, LRANK1, FIGLER7

Related Genes

#	Gene Symbol	Number of hits
1	GPI	1 hits
2	GSTA1	1 hits
3	GSTCD	1 hits
4	PTPRC	1 hits

Related Sentences

#	PMID	Sentence
1	11145714	Mutations in the common gamma-chain (gamma(c)) of cytokine receptors, including those for IL-2, IL-4, IL-7, IL-9, and IL-15, are responsible for an X-linked form of the disease, while mutations of several other genes, including Janus-associated kinase-3, may cause autosomal recessive forms of SCID.
2	11145714	We report here that a homozygous 6-bp deletion in the gene encoding CD45 (PTPRC, gene map locus 1q31-32), which results in a loss of glutamic acid 339 and tyrosine 340 in the first fibronectin type III module of the extracellular domain of CD45, is associated with failure of surface expression of CD45 and SCID.
3	11223124	The proteins encoded by this family of genes contain putative N-linked glycosylation sites, an amino terminal secretory signal, a hydrophobic carboxy terminal sequence characteristic of GPI-anchored proteins and fibronectin type III motifs.
4	22521850	The TSOL16, TSOL45-1A and TSOL45-1B recombinant antigens, each consisting of fibronectin type III (FnIII) domain S, were produced as fusion proteins with glutathione S-transferase (GST) and maltose binding protein (MBP).