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Gene Information

Gene symbol: LSM2

Gene name: LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)

HGNC ID: 13940

Synonyms: G7b, YBL026W

Related Genes

# Gene Symbol Number of hits
1 BCL11B 1 hits
2 RN7SK 1 hits

Related Sentences

# PMID Sentence
1 24623795 CTIP2 represses P-TEFb activity in a complex containing 7SK RNA and HEXIM1.
2 24623795 Here we show global synergy between CTIP2 and the 7SK-binding chromatin master-regulator HMGA1 in terms of P-TEFb-dependent endogenous and HIV-1 gene expression regulation.
3 24623795 While CTIP2 and HMGA1 concordingly repress the expression of cellular 7SK-dependent P-TEFb targets, the simultaneous knock-down of CTIP2 and HMGA1 also results in a boost in Tat-dependent and independent HIV-1 promoter activity.
4 24623795 Chromatin immunoprecipitation experiments reveal a significant loss of CTIP2/7SK/P-TEFb snRNP recruitment to cellular gene promoters and the HIV-1 promoter on HMGA1 knock-down.
5 24623795 Our findings not only provide insights into a recruiting mechanism for the inactive 7SK/P-TEFb snRNP, but may also contribute to a better understanding of viral latency.
6 24623795 CTIP2 represses P-TEFb activity in a complex containing 7SK RNA and HEXIM1.
7 24623795 Here we show global synergy between CTIP2 and the 7SK-binding chromatin master-regulator HMGA1 in terms of P-TEFb-dependent endogenous and HIV-1 gene expression regulation.
8 24623795 While CTIP2 and HMGA1 concordingly repress the expression of cellular 7SK-dependent P-TEFb targets, the simultaneous knock-down of CTIP2 and HMGA1 also results in a boost in Tat-dependent and independent HIV-1 promoter activity.
9 24623795 Chromatin immunoprecipitation experiments reveal a significant loss of CTIP2/7SK/P-TEFb snRNP recruitment to cellular gene promoters and the HIV-1 promoter on HMGA1 knock-down.
10 24623795 Our findings not only provide insights into a recruiting mechanism for the inactive 7SK/P-TEFb snRNP, but may also contribute to a better understanding of viral latency.