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Gene Information

Gene symbol: LYN

Gene name: v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

HGNC ID: 6735

Synonyms: JTK8

Related Genes

# Gene Symbol Number of hits
1 CD4 1 hits
2 CSF1 1 hits
3 FGR 1 hits
4 GPI 1 hits
5 HCK 1 hits
6 LCK 1 hits
7 PTK2B 1 hits

Related Sentences

# PMID Sentence
1 11694268 HIV-SUgp120 (HIV-surface glycoprotein), T-cell receptor (TCR)-CD4+ and co-receptors promote aggregation of these lipid "rafts" which concentrate the Src family tyrosine kinases SFKs (PTK, Lyn, Fyn, Lck), GPI (glycosyl phosphatidylinositol)-anchored proteins, and phosphatidylinositol kinases PI(3)K and PI(4)K, inducing cell signalling.
2 11694268 Lipodystrophy (LD), consists of peripheral lipoatrophy associated with central fat accumulation (called "crixbelly" and "buffalo hump"), insulin resistance, elevation of very low density lipoproteins, decrease in high density lipoproteins and inhibition of adipocyte differentiation.
3 11708879 Non-immunogenic murine hepatocellular carcinoma Hepa1-6 cells expressing the membrane form of macrophage colony stimulating factor are rejected in vivo and lead to CD8+ T-cell immunity against the parental tumor.
4 11708879 Macrophages derived from Hck(-/-)Fgr(-/-) and Lyn(-/-) triple knockout mice, which are incapable of performing phagocytosis, failed to kill the mM-CSF transduced cells.