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Gene Information

Gene symbol: MAPKAP1

Gene name: mitogen-activated protein kinase associated protein 1

HGNC ID: 18752

Synonyms: MGC2745, SIN1, MIP1

Related Genes

# Gene Symbol Number of hits
1 CCL2 1 hits
2 CCL3 1 hits
3 CCL5 1 hits
4 TLR3 1 hits
5 TLR7 1 hits
6 TLR9 1 hits

Related Sentences

# PMID Sentence
1 20451253 Production of monocyte chemoattractant protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1 (MIP-1/CCL3) and regulated on activation, normal T cell expressed and secreted (RANTES/CCL5), were determined in cell culture supernatants by ELISA or cytokine cytometric bead array.
2 20451253 Pharmacological inhibitors of p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), nuclear factor-kappaB (NF-kB) and phosphatidylinositol 3-kinase (PI3K), were used to investigate the role of signaling pathways.
3 20451253 TLR agonists induced significantly elevated MCP-1, RANTES, and MIP-1.
4 20451253 Production of RANTES and MIP-1 was particularly prominent after stimulation of DCs with TLR3 (Poly(I:C)), and TLR7/8 (R848) or TLR9 (CpG ODN) agonists, respectively.
5 20451253 A positive role was identified for NF-kB, PI3K and ERK, whereas JNK had a negative regulatory effect on chemokine production in DCs.
6 20451253 Positive and negative regulatory roles for the p38 MAPK pathway were observed.
7 20451253 Production of monocyte chemoattractant protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1 (MIP-1/CCL3) and regulated on activation, normal T cell expressed and secreted (RANTES/CCL5), were determined in cell culture supernatants by ELISA or cytokine cytometric bead array.
8 20451253 Pharmacological inhibitors of p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), nuclear factor-kappaB (NF-kB) and phosphatidylinositol 3-kinase (PI3K), were used to investigate the role of signaling pathways.
9 20451253 TLR agonists induced significantly elevated MCP-1, RANTES, and MIP-1.
10 20451253 Production of RANTES and MIP-1 was particularly prominent after stimulation of DCs with TLR3 (Poly(I:C)), and TLR7/8 (R848) or TLR9 (CpG ODN) agonists, respectively.
11 20451253 A positive role was identified for NF-kB, PI3K and ERK, whereas JNK had a negative regulatory effect on chemokine production in DCs.
12 20451253 Positive and negative regulatory roles for the p38 MAPK pathway were observed.
13 20451253 Production of monocyte chemoattractant protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1 (MIP-1/CCL3) and regulated on activation, normal T cell expressed and secreted (RANTES/CCL5), were determined in cell culture supernatants by ELISA or cytokine cytometric bead array.
14 20451253 Pharmacological inhibitors of p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), nuclear factor-kappaB (NF-kB) and phosphatidylinositol 3-kinase (PI3K), were used to investigate the role of signaling pathways.
15 20451253 TLR agonists induced significantly elevated MCP-1, RANTES, and MIP-1.
16 20451253 Production of RANTES and MIP-1 was particularly prominent after stimulation of DCs with TLR3 (Poly(I:C)), and TLR7/8 (R848) or TLR9 (CpG ODN) agonists, respectively.
17 20451253 A positive role was identified for NF-kB, PI3K and ERK, whereas JNK had a negative regulatory effect on chemokine production in DCs.
18 20451253 Positive and negative regulatory roles for the p38 MAPK pathway were observed.