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Gene Information

Gene symbol: MARCH8

Gene name: membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

HGNC ID: 23356

Synonyms: c-MIR, MARCH-VIII, RNF178

Related Genes

#	Gene Symbol	Number of hits
1	IRAK1	1 hits
2	MIRN221	1 hits
3	MXD1	1 hits
4	NFKB1	1 hits
5	TLR2	1 hits

Related Sentences

#	PMID	Sentence
1	15039560	Several native and heavy-atom data sets have been collected from Pvs25 and methylated Pvs25 crystals for use in MAD or MIR techniques.
2	23845179	IL4 and IFNalpha generation of dendritic cells reveals great migratory potential and NFkB and cJun expression in IL4DCs.
3	23845179	Dendritic cells (DCs) recently revealed as a potent tumor vaccine component, are commonly differentiated from monocytes by cultivation with IL-4 and GM-CSF.
4	23845179	The aim of this study was to compare the functionality and phenotypic characterization of monocyte-derived DC generated by IL-4 (IL4DC) and IFNalpha (IFNalphaDC) modified protocols.
5	23845179	We herein investigated the molecular mechanism underlying the parameters previously described, as the relative expression of NF-kB p65, c-fos and c-jun, transcription factors.
6	23845179	Our results demonstrated that IL4DC presented a stable phenotype, an increase in migratory capacity and NF-KB activation, in addition to lower levels of miR-146 a and miR-221.
7	25955717	Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway.
8	25955717	Consistent with this observation, miR-UL112-3p transfection significantly reduced the expression of multiple cytokines (IL-1β, IL-6 and IL-8) upon stimulation with a TLR2 agonist.
9	25955717	Finally, miR-UL112-3p transfection significantly inhibited the TLR2-induced post-translational activation of IRAK1, a kinase located in the upstream section of the TLR2/NFκB signaling axis.