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Gene Information

Gene symbol: MARCH9

Gene name: membrane-associated ring finger (C3HC4) 9

HGNC ID: 25139

Synonyms: RNF179, FLJ36578

Related Genes

# Gene Symbol Number of hits
1 MARCH4 1 hits

Related Sentences

# PMID Sentence
1 14722266 Poxviruses and gamma-2 herpesviruses share the K3 family of viral immune evasion proteins that inhibit the surface expression of glycoproteins such as major histocompatibility complex class I (MHC-I), B7.2, ICAM-1, and CD95(Fas).
2 14722266 K3 family proteins contain an amino-terminal PHD/LAP or RING-CH domain followed by two transmembrane domains.
3 14722266 Two closely related proteins, MARCH-IV and MARCH-IX, reduced surface expression of MHC-I molecules.
4 14722266 In the presence of MARCH-IV or MARCH-IX, MHC-I was ubiquitinated and rapidly internalized by endocytosis, whereas MHC-I molecules lacking lysines in their cytoplasmic tail were resistant to downregulation.
5 14722266 Poxviruses and gamma-2 herpesviruses share the K3 family of viral immune evasion proteins that inhibit the surface expression of glycoproteins such as major histocompatibility complex class I (MHC-I), B7.2, ICAM-1, and CD95(Fas).
6 14722266 K3 family proteins contain an amino-terminal PHD/LAP or RING-CH domain followed by two transmembrane domains.
7 14722266 Two closely related proteins, MARCH-IV and MARCH-IX, reduced surface expression of MHC-I molecules.
8 14722266 In the presence of MARCH-IV or MARCH-IX, MHC-I was ubiquitinated and rapidly internalized by endocytosis, whereas MHC-I molecules lacking lysines in their cytoplasmic tail were resistant to downregulation.