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Gene Information
Gene symbol: MDC1
Gene name: mediator of DNA-damage checkpoint 1
HGNC ID: 21163
Synonyms: NFBD1, KIAA0170, Em:AB023051.5
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADAM22 | 1 hits |
| 2 | CD1C | 1 hits |
| 3 | ITGAX | 1 hits |
| 4 | THBD | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19049809 | In this study, we report a novel direct ex vivo 11-color flow cytometric assay that combines subset identification with analysis of activation status and endocytic ability of three major PBDC subsets (CD1c(+)CD11c(+) "MDC1," CD141(+)CD11c(+) "MDC2," and CD303(+)CD11c(-) "PDC") within a single platform. |
| 2 | 19049809 | As expected, PBDC identified by this assay express low levels of CD40 and CD86 directly ex vivo, and significantly upregulate expression of these molecules upon stimulation with toll-like receptor ligands LPS and CpG oligonucleotides. |
| 3 | 19049809 | In addition, PDC internalize FITC-labeled dextran poorly in comparison to MDC1 and MDC2 subsets. |
| 4 | 19049809 | Furthermore, the combination of surface markers used in this assay reveals a previously unreported CD4(+)CD11c(+)CD303(-)CD1c(-)CD141(-) cell population. |
| 5 | 19049809 | In this study, we report a novel direct ex vivo 11-color flow cytometric assay that combines subset identification with analysis of activation status and endocytic ability of three major PBDC subsets (CD1c(+)CD11c(+) "MDC1," CD141(+)CD11c(+) "MDC2," and CD303(+)CD11c(-) "PDC") within a single platform. |
| 6 | 19049809 | As expected, PBDC identified by this assay express low levels of CD40 and CD86 directly ex vivo, and significantly upregulate expression of these molecules upon stimulation with toll-like receptor ligands LPS and CpG oligonucleotides. |
| 7 | 19049809 | In addition, PDC internalize FITC-labeled dextran poorly in comparison to MDC1 and MDC2 subsets. |
| 8 | 19049809 | Furthermore, the combination of surface markers used in this assay reveals a previously unreported CD4(+)CD11c(+)CD303(-)CD1c(-)CD141(-) cell population. |