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Gene Information
Gene symbol: MIPEP
Gene name: mitochondrial intermediate peptidase
HGNC ID: 7104
Synonyms: MIP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AIFM1 | 1 hits |
| 2 | BAX | 1 hits |
| 3 | CCL18 | 1 hits |
| 4 | CCL4 | 1 hits |
| 5 | CD40 | 1 hits |
| 6 | CYCS | 1 hits |
| 7 | IFN1 | 1 hits |
| 8 | IFNA1 | 1 hits |
| 9 | IL12A | 1 hits |
| 10 | IL6 | 1 hits |
| 11 | TNF | 1 hits |
| 12 | UBASH3B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16037410 | Dendritic cells differentiated in the presence of IFN-{beta} and IL-3 are potent inducers of an antigen-specific CD8+ T cell response. |
| 2 | 16037410 | Classically, mature monocyte-derived DC are generated in vitro in the presence of interleukin (IL)-4, granulocyte macrophage-colony stimulating factor, and inflammatory cytokines (G4-DC). |
| 3 | 16037410 | Recently, it has been described that DC can also be generated in the presence of IL-3 and interferon (IFN)-beta and that these DC are efficiently matured using polyriboinosinic polyribocytidylic acid (I3-DC). |
| 4 | 16037410 | Phenotypic characterization of the DC revealed differences in the expression of the monocyte marker CD14 and the maturation marker CD83. |
| 5 | 16037410 | Low expression of CD14 and high expression of CD83 characterized G4-DC, whereas I3-DC displayed intermediate expression of CD14 and CD83. |
| 6 | 16037410 | Upon CD40 ligation, G4-DC produced lower amounts of IFN-alpha and pulmonary and activation-regulated chemokine, similar amounts of IL-6, macrophage-inflammatory protein (MIP)-1alpha, and MIP-1beta, and higher amounts of IL-12 p70, tumor necrosis factor alpha, and MIP-3beta than I3-DC. |
| 7 | 16037410 | Finally, in vitro stimulations showed that fresh and frozen peptide-loaded I3-DC are more potent inducers of Melan-A-specific CD8(+) T cell responses than G4-DC. |
| 8 | 21347304 | It is demonstrated that the MIP cell-free supernatant induced apoptosis is mitochondria-mediated and caspase independent and involves mitochondrial translocation of Bax and subsequent release of AIF and cytochrome c from the mitochondria. |