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Gene Information
Gene symbol: MMP14
Gene name: matrix metallopeptidase 14 (membrane-inserted)
HGNC ID: 7160
Synonyms: MT1-MMP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADAM8 | 1 hits |
| 2 | AQP9 | 1 hits |
| 3 | CCL17 | 1 hits |
| 4 | CCL8 | 1 hits |
| 5 | KDR | 1 hits |
| 6 | LTB4R | 1 hits |
| 7 | MMP2 | 1 hits |
| 8 | MMP9 | 1 hits |
| 9 | NOS2A | 1 hits |
| 10 | TGFA | 1 hits |
| 11 | TGFB1 | 1 hits |
| 12 | TIMP1 | 1 hits |
| 13 | TIMP2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16294321 | We compared the levels of expression of a number of molecules involved in tumor metastasis, which included transforming growth factor-beta1 (TGF-beta1), E-cadherin, matrix metalloproteinases (MMPs): MT1-MMP, MMP-2, MMP-9, their tissue inhibitors (TIMPs): TIMP-1/TIMP-2, and pro-angiogenic factors CD31, VEGF-R2, and iNOS between primary and metastatic tumors by real-time RT-PCR and immunohistochemistry. |
| 2 | 16294321 | In the metastatic tumors, levels of MT1-MMP, MMP-2, and MMP-9 were significantly elevated (P < 0.001), while levels of TIMP-1/TIMP-2 and E-cadherin were decreased (P < 0.001) compared to control or primary tumors. |
| 3 | 16294321 | Levels of CD31, VEGF-R2, and iNOS were also significantly elevated in the metastatic lesions (P < 0.001). |
| 4 | 16294321 | We compared the levels of expression of a number of molecules involved in tumor metastasis, which included transforming growth factor-beta1 (TGF-beta1), E-cadherin, matrix metalloproteinases (MMPs): MT1-MMP, MMP-2, MMP-9, their tissue inhibitors (TIMPs): TIMP-1/TIMP-2, and pro-angiogenic factors CD31, VEGF-R2, and iNOS between primary and metastatic tumors by real-time RT-PCR and immunohistochemistry. |
| 5 | 16294321 | In the metastatic tumors, levels of MT1-MMP, MMP-2, and MMP-9 were significantly elevated (P < 0.001), while levels of TIMP-1/TIMP-2 and E-cadherin were decreased (P < 0.001) compared to control or primary tumors. |
| 6 | 16294321 | Levels of CD31, VEGF-R2, and iNOS were also significantly elevated in the metastatic lesions (P < 0.001). |
| 7 | 23685352 | Other genes associated with asthma including FcγRIIb, MMP-14, CCL-8, CCL-17, ADAM-8, LTBR1, aquaporin-9 and IL-7R were also expressed at higher levels in Ova sensitized/challenged animals when compared to BAMs isolated from control animals. |
| 8 | 23685352 | Eotaxin 2 (CCL-24), which is known to influence eosinophil migration, was highly up-regulated in BAMs, but not Eotaxin-1 (CCL-11). |
| 9 | 23685352 | Conversely, lung interstitial macrophages expressed high levels of CCL-11, but not CCL-24. |