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Gene Information

Gene symbol: MUC13

Gene name:

HGNC ID:

Related Genes

# Gene Symbol Number of hits
1 MUC1 1 hits
2 MUC12 1 hits
3 MUC15 1 hits
4 MUC16 1 hits
5 MUC17 1 hits
6 MUC2 1 hits
7 MUC3B 1 hits
8 MUC4 1 hits
9 MUC5AC 1 hits
10 MUC5B 1 hits
11 MUC6 1 hits
12 MUC7 1 hits
13 MUC8 1 hits

Related Sentences

# PMID Sentence
1 15000151 There are two structurally and functionally distinct classes of mucins: secreted gel-forming mucins (MUC2, MUC5AC, MUC5B, and MUC6) and transmembrane mucins (MUC1, MUC3A, MUC3B, MUC4, MUC12, MUC17), although the products of some MUC genes do not fit well into either class (MUC7, MUC8, MUC9, MUC13, MUC15, MUC16).
2 15000151 Expression of MUC2 secreted gel-forming mucin is generally decreased in colorectal adenocarcinoma, but preserved in mucinous carcinomas, a distinct subtype of colon cancer associated with microsatellite instability.
3 15000151 Another secreted gel-forming mucin, MUC5AC, a product of normal gastric mucosa, is absent from normal colon, but frequently present in colorectal adenomas and colon cancers.
4 15000151 The endogenous galactoside-binding protein galectin-3, which is expressed at higher levels in colon cancers than normal colon, binds to colon cancer mucin as well as other glycoproteins.
5 15000151 Interference of the binding of selectins and galectin-3 to mucin may show therapeutic or preventative promise for colon cancer.
6 24866791 In the later stages of infection, mRNA expression of H(+)/K(+)-ATPase α/β and KCNQ1 decreased, whereas the expression of Muc4, Tff2, Dmbt1, and polymeric immunoglobulin receptor (pIgR) increased starting at 16 weeks postinfection onwards, suggesting the existence of spasmolytic polypeptide-expressing metaplasia in the fundus of the stomach.
7 24866791 Our findings indicate that H. heilmannii infection causes severe gastric pathologies and alterations in the expression pattern of gastric mucins, such as Muc6 and Muc13, as well as disrupting gastric homeostasis by inducing the loss of parietal cells, resulting in the development of mucous metaplasia.