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Gene Information

Gene symbol: MUC3B

Gene name: mucin 3B, cell surface associated

HGNC ID: 13384

Related Genes

# Gene Symbol Number of hits
1 MUC1 1 hits
2 MUC12 1 hits
3 MUC13 1 hits
4 MUC15 1 hits
5 MUC16 1 hits
6 MUC17 1 hits
7 MUC2 1 hits
8 MUC4 1 hits
9 MUC5AC 1 hits
10 MUC5B 1 hits
11 MUC6 1 hits
12 MUC7 1 hits
13 MUC8 1 hits

Related Sentences

# PMID Sentence
1 15000151 There are two structurally and functionally distinct classes of mucins: secreted gel-forming mucins (MUC2, MUC5AC, MUC5B, and MUC6) and transmembrane mucins (MUC1, MUC3A, MUC3B, MUC4, MUC12, MUC17), although the products of some MUC genes do not fit well into either class (MUC7, MUC8, MUC9, MUC13, MUC15, MUC16).
2 15000151 Expression of MUC2 secreted gel-forming mucin is generally decreased in colorectal adenocarcinoma, but preserved in mucinous carcinomas, a distinct subtype of colon cancer associated with microsatellite instability.
3 15000151 Another secreted gel-forming mucin, MUC5AC, a product of normal gastric mucosa, is absent from normal colon, but frequently present in colorectal adenomas and colon cancers.
4 15000151 The endogenous galactoside-binding protein galectin-3, which is expressed at higher levels in colon cancers than normal colon, binds to colon cancer mucin as well as other glycoproteins.
5 15000151 Interference of the binding of selectins and galectin-3 to mucin may show therapeutic or preventative promise for colon cancer.
6 23827311 Interaction of this protozoan parasite with the intestine is mediated through the binding of the trophozoite stage to intestinal mucin and epithelium via a galactose and N-acetyl-d-galactosamine (Gal/GalNAc) lectin comprised of a disulfide linked heavy (ca. 180 kDa) and light chain (ca. 35 kDa) and a noncovalently bound intermediate subunit (ca. 150 kDa).
7 24478066 EatA, an immunogenic protective antigen of enterotoxigenic Escherichia coli, degrades intestinal mucin.