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Gene Information
Gene symbol: MUC5B
Gene name: mucin 5B, oligomeric mucus/gel-forming
HGNC ID: 7516
Synonyms: MG1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | C6orf205 | 1 hits |
| 2 | MUC1 | 1 hits |
| 3 | MUC12 | 1 hits |
| 4 | MUC13 | 1 hits |
| 5 | MUC15 | 1 hits |
| 6 | MUC16 | 1 hits |
| 7 | MUC17 | 1 hits |
| 8 | MUC2 | 1 hits |
| 9 | MUC20 | 1 hits |
| 10 | MUC3A | 1 hits |
| 11 | MUC3B | 1 hits |
| 12 | MUC4 | 1 hits |
| 13 | MUC5AC | 1 hits |
| 14 | MUC6 | 1 hits |
| 15 | MUC7 | 1 hits |
| 16 | MUC8 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10608618 | Seventeen human ovarian carcinoma cell lines were evaluated for their expression of mucin core polypeptide mRNAs (MUC1, MUC2, MUC3, MUC5AC, MUC5B, and MUC6) by the reverse transcription-polymerase chain reaction. |
| 2 | 10608618 | Mucin-associated carbohydrate epitopes were not detected on three of four serous adenocarcinoma cell lines, although MUC1 and MUC2 mRNAs were detected in all of them. |
| 3 | 12964025 | DCs from 14 patients with advanced or metastatic breast or lung cancer (9 positive for MUC1 and 5 negative for MUC1) were loaded with MUC1 antigens or tumor lysate and used for therapeutic vaccination. |
| 4 | 12964025 | However, MUC1-negative patients did not respond to DC vaccines, with the exception of 1 case with MAGE3-positive lung cancer. |
| 5 | 15000151 | There are two structurally and functionally distinct classes of mucins: secreted gel-forming mucins (MUC2, MUC5AC, MUC5B, and MUC6) and transmembrane mucins (MUC1, MUC3A, MUC3B, MUC4, MUC12, MUC17), although the products of some MUC genes do not fit well into either class (MUC7, MUC8, MUC9, MUC13, MUC15, MUC16). |
| 6 | 15000151 | Expression of MUC2 secreted gel-forming mucin is generally decreased in colorectal adenocarcinoma, but preserved in mucinous carcinomas, a distinct subtype of colon cancer associated with microsatellite instability. |
| 7 | 15000151 | Another secreted gel-forming mucin, MUC5AC, a product of normal gastric mucosa, is absent from normal colon, but frequently present in colorectal adenomas and colon cancers. |
| 8 | 15000151 | The endogenous galactoside-binding protein galectin-3, which is expressed at higher levels in colon cancers than normal colon, binds to colon cancer mucin as well as other glycoproteins. |
| 9 | 15000151 | Interference of the binding of selectins and galectin-3 to mucin may show therapeutic or preventative promise for colon cancer. |
| 10 | 17509526 | Solution structure of the all L- and D-amino acid-substituted mucin 2 epitope peptides. |
| 11 | 17509526 | High-molecular-weight mucin 2 (MUC2) glycoproteins show an aberrant glycosylation pattern when expressed in human colon carcinoma: the oligosaccharide chains are shorter and some are missing. |
| 12 | 25977598 | Our data indicate that the MUC expression by RSV and hMPV differs significantly, as we observed a stronger induction of MUC8, MUC15, MUC20, MUC21, and MUC22 by RSV infection while the expression of MUC1, MUC2, and MUC5B was dominated by the infection with hMPV. |