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Gene Information
Gene symbol: NANOG
Gene name: Nanog homeobox
HGNC ID: 20857
Synonyms: FLJ12581, FLJ40451
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ABCG2 | 1 hits |
| 2 | ALPI | 1 hits |
| 3 | CD44 | 1 hits |
| 4 | POU5F1 | 1 hits |
| 5 | PROM1 | 1 hits |
| 6 | SLC25A25 | 1 hits |
| 7 | SOX2 | 1 hits |
| 8 | TBX1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24874290 | The granulocyte macrophage-colony stimulating factor surface modified MB49 bladder cancer stem cells vaccine against metastatic bladder cancer. |
| 2 | 24874290 | MCSCs possessed higher expression of CD133, CD44, OCT4, NANOG, and ABCG2, the ability of differentiation, higher proliferative abilities, lower susceptibility to chemotherapy, greater migration in vitro, and stronger tumorigenic abilities in vivo. |
| 3 | 24874290 | Then streptavidin-mouse granulocyte macrophage-colony stimulating factor (SA-mGM-CSF) MCSCs vaccine was prepared. |
| 4 | 24874290 | The level of immunoglobulin G and the ratio of dendritic cells and CD4(+) and CD8(+) T cells were highest in the experimental group when compared to those in other four control groups, as well as for the cytotoxicity assay. |
| 5 | 25553348 | Then the cells were cultured on inactivated mouse SNL feeder cells in the presence of LIF, IGF-1, bFGF, CNTF, OSM, SCF, Il-6, and Il-11 growth factors. |
| 6 | 25553348 | Furthermore, the expression of pluripotency (cPouV, Sox2, and Nanog) and cell lineage specific (Cvh, Brachyury, and Gata6) gene markers was evaluated at the level of mRNA using quantitative RT-PCR. |
| 7 | 25553348 | The stemness of embryonic cells has been approved by the activity of the alkaline phosphatase, presence of the SSEA-4, and TRA-1-60 protein, and expression of the molecular marker (cPouV, Nanog, and Sox-2) genes. |
| 8 | 25553348 | Then the cells were cultured on inactivated mouse SNL feeder cells in the presence of LIF, IGF-1, bFGF, CNTF, OSM, SCF, Il-6, and Il-11 growth factors. |
| 9 | 25553348 | Furthermore, the expression of pluripotency (cPouV, Sox2, and Nanog) and cell lineage specific (Cvh, Brachyury, and Gata6) gene markers was evaluated at the level of mRNA using quantitative RT-PCR. |
| 10 | 25553348 | The stemness of embryonic cells has been approved by the activity of the alkaline phosphatase, presence of the SSEA-4, and TRA-1-60 protein, and expression of the molecular marker (cPouV, Nanog, and Sox-2) genes. |
| 11 | 25637356 | GLP and G9a are major H3K9 dimethylases and are essential for mouse early embryonic development. |
| 12 | 25637356 | GLP and G9a both harbor ankyrin repeat domains that are capable of binding H3K9 methylation. |
| 13 | 25637356 | Here, we report that the histone methyltransferase activities of GLP and G9a are stimulated by neighboring nucleosomes that are premethylated at H3K9. |
| 14 | 25637356 | These stimulation events function in cis and are dependent on the H3K9 methylation binding activities of ankyrin repeat domains of GLP and G9a. |
| 15 | 25637356 | In mouse embryonic stem cells (ESCs) harboring a mutant GLP that lacks H3K9me1-binding activity, critical pluripotent genes, including Oct4 and Nanog, display inefficient establishment of H3K9me2 and delayed gene silencing during differentiation. |
| 16 | 25637356 | Collectively, our study reveals a new activation mechanism for GLP and G9a that plays an important role in ESC differentiation and mouse viability. |