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Gene Information
Gene symbol: NDUFS4
Gene name: NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
HGNC ID: 7711
Synonyms: AQDQ, CI-18
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NDUFA13 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25550785 | Overexpression of GRIM-19, a mitochondrial respiratory chain complex I protein, suppresses hepatocellular carcinoma growth. |
| 2 | 25550785 | AKT1, pAKT1, cyclinD1, CDK4, PCNA, Bax, Bcl-2, cleaved caspase-9, cleaved caspase-3, and cytochrome C were detected by Western blot and immunofluorescence. |
| 3 | 25550785 | We also found that AKT1 expression and phosphorylation were regulated by the expression of GRIM-19. |
| 4 | 25550785 | Collectively, our study demonstrated that GRIM-19 overexpression suppressed HCC growth and downregulated AKT1 expression, suggesting that GRIM-19 might play a crucial role in hepatocarcinogenesis through negatively regulating the PI3K/AKT signaling pathway. |