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Gene Information
Gene symbol: NEU2
Gene name: sialidase 2 (cytosolic sialidase)
HGNC ID: 7759
Synonyms: SIAL2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NEU1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9250801 | Six months after vaccination GMT for neuraminidase 1 (N1) increased when compared with the second sampling; for neuraminidase 2 (N2) and neuraminidase B (NB) it was slightly lower. |
| 2 | 22403397 | NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not. |
| 3 | 22403397 | Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4. |
| 4 | 22403397 | Western analyses indicated NEU1 and -3 protein expression. |
| 5 | 22403397 | Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively. |
| 6 | 22403397 | NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not. |
| 7 | 22403397 | Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia. |
| 8 | 22403397 | These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3. |
| 9 | 22403397 | NEU1 restrains EC migration, whereas NEU3 does not. |