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PMID |
Sentence |
1 |
22403397
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NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
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2 |
22403397
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Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
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3 |
22403397
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Western analyses indicated NEU1 and -3 protein expression.
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4 |
22403397
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Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
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5 |
22403397
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NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
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6 |
22403397
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Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
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7 |
22403397
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These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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8 |
22403397
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NEU1 restrains EC migration, whereas NEU3 does not.
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9 |
22403397
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NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
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10 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
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11 |
22403397
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Western analyses indicated NEU1 and -3 protein expression.
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12 |
22403397
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Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
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13 |
22403397
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NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
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14 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
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15 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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16 |
22403397
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NEU1 restrains EC migration, whereas NEU3 does not.
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17 |
22403397
|
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
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18 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
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19 |
22403397
|
Western analyses indicated NEU1 and -3 protein expression.
|
20 |
22403397
|
Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
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21 |
22403397
|
NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
|
22 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
|
23 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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24 |
22403397
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NEU1 restrains EC migration, whereas NEU3 does not.
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25 |
22403397
|
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
|
26 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
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27 |
22403397
|
Western analyses indicated NEU1 and -3 protein expression.
|
28 |
22403397
|
Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
|
29 |
22403397
|
NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
|
30 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
|
31 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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32 |
22403397
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NEU1 restrains EC migration, whereas NEU3 does not.
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33 |
22403397
|
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
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34 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
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35 |
22403397
|
Western analyses indicated NEU1 and -3 protein expression.
|
36 |
22403397
|
Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
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37 |
22403397
|
NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
|
38 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
|
39 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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40 |
22403397
|
NEU1 restrains EC migration, whereas NEU3 does not.
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41 |
22403397
|
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
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42 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
|
43 |
22403397
|
Western analyses indicated NEU1 and -3 protein expression.
|
44 |
22403397
|
Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
|
45 |
22403397
|
NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
|
46 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
|
47 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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48 |
22403397
|
NEU1 restrains EC migration, whereas NEU3 does not.
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49 |
22403397
|
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
|
50 |
22403397
|
Using real time RT-PCR to detect mRNAs for the four known mammalian sialidases, NEU1, -2, -3, and -4, NEU1 mRNA was expressed at levels 2700-fold higher that those found for NEU2, -3, or -4.
|
51 |
22403397
|
Western analyses indicated NEU1 and -3 protein expression.
|
52 |
22403397
|
Prior siRNA-mediated knockdown of NEU1 and NEU3 each decreased EC sialidase activity for 4-MU-NANA by >65 and >17%, respectively, and for the ganglioside mixture by 0 and 40%, respectively.
|
53 |
22403397
|
NEU1 overexpression in ECs reduced their migration into a wound by >40%, whereas NEU3 overexpression did not.
|
54 |
22403397
|
Immunohistochemical studies of normal human tissues immunolocalized NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.
|
55 |
22403397
|
These combined data indicate that human lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.
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56 |
22403397
|
NEU1 restrains EC migration, whereas NEU3 does not.
|