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Gene Information

Gene symbol: NFKB2

Gene name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

HGNC ID: 7795

Synonyms: LYT-10, p52, p105, NF-kB2

Related Genes

# Gene Symbol Number of hits
1 BCL2A1 1 hits
2 CASP2 1 hits
3 CASP8 1 hits
4 CAST 1 hits
5 CCL4 1 hits
6 CDK2 1 hits
7 CFLAR 1 hits
8 GADD45B 1 hits
9 IL1B 1 hits
10 NFKB1 1 hits
11 PIM2 1 hits
12 RELA 1 hits
13 SOD2 1 hits
14 TNFAIP3 1 hits
15 TNFRSF10C 1 hits
16 TNFRSF10D 1 hits
17 TNFSF10 1 hits
18 VEGFA 1 hits
19 XIAP 1 hits

Related Sentences

# PMID Sentence
1 16379000 Upregulated transcripts correlated with genes implicated in immune responses, including those encoding interleukin-1 receptor 2 (IL-1R2), IL-6, ISG-15, CD-80, and TNFSF7.
2 16379000 NYVAC infection also stimulated the expression of NF-kappaB1 and NF-kappaB2 as well as that of NF-kappaB target genes.
3 22986450 Specific targets in this category included genes asso-ciated with the intrinsic and extrinsic apoptotic pathways (CFLAR, TNFAIP3, TNFRSF10D, SOD2, BCL2A1, BIRC4, PIM2, TNFSF10, TNFRSF10C, CASP2 and CASP8) and genes that act via the NFĸB pathway and other mechanisms to prolong cell viability (NFKB1, NFKB2 and RELA, IL1B, CAST, CDK2,GADD45B, BCL3, BIRC3, CDK2, IL1A, PBEF1, IL6, CXCL1, CCL4 and VEGF).
4 22986450 Moreover, we demonstrate that the X-linked inhibitor of apoptosis protein remained abundant in polymorphonuclear leukocytes over 48 h of LVS infection, whereas BAX mRNA and protein were progressively downregulated.