Gene Information
Gene symbol: NLRC5
Gene name: NLR family, CARD domain containing 5
HGNC ID: 29933
Synonyms: NOD27, CLR16.1, FLJ21709
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
26174952
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Here, we show porin differentially regulated splenic marginal zone (MZ) and follicular zone (FO) B cell responses in contrast to other classical TLR2-ligands FSL-1 and Pam3CSK4.
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2 |
26174952
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The protein up-regulated TLR2 and TLR6 and stimulated the activation and costimulatory molecules on FO B cells skewing the cells toward TLR-dependent type-1 cytokine response.
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3 |
26174952
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These cells responded to porin by expressing toll-interacting protein (TOLLIP), the TLR2 and -4 signaling inhibitor along with stimulation of the intracellular pathogen recognition receptor NLR caspase recruitment domain containing protein 5 (NLRC5).
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4 |
26174952
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The CD1d(hi) MZ B cells released IL-10 unequivocally demonstrating regulatory B cell feature.
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5 |
26174952
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Immunization with porin also resulted in transient IL-10 expression by the CD19(+)CD21(hi) B cells prior to plasma cell formation.
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