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Gene Information

Gene symbol: NLRC5

Gene name: NLR family, CARD domain containing 5

HGNC ID: 29933

Synonyms: NOD27, CLR16.1, FLJ21709

Related Genes

# Gene Symbol Number of hits
1 TLR2 1 hits
2 TLR4 1 hits
3 TOLLIP 1 hits

Related Sentences

# PMID Sentence
1 26174952 Here, we show porin differentially regulated splenic marginal zone (MZ) and follicular zone (FO) B cell responses in contrast to other classical TLR2-ligands FSL-1 and Pam3CSK4.
2 26174952 The protein up-regulated TLR2 and TLR6 and stimulated the activation and costimulatory molecules on FO B cells skewing the cells toward TLR-dependent type-1 cytokine response.
3 26174952 These cells responded to porin by expressing toll-interacting protein (TOLLIP), the TLR2 and -4 signaling inhibitor along with stimulation of the intracellular pathogen recognition receptor NLR caspase recruitment domain containing protein 5 (NLRC5).
4 26174952 The CD1d(hi) MZ B cells released IL-10 unequivocally demonstrating regulatory B cell feature.
5 26174952 Immunization with porin also resulted in transient IL-10 expression by the CD19(+)CD21(hi) B cells prior to plasma cell formation.