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Gene Information
Gene symbol: NPC1
Gene name: Niemann-Pick disease, type C1
HGNC ID: 7897
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CSF1 | 1 hits |
| 2 | CXCL11 | 1 hits |
| 3 | CXCL9 | 1 hits |
| 4 | GP2 | 1 hits |
| 5 | GTPBP1 | 1 hits |
| 6 | HAVCR1 | 1 hits |
| 7 | IFRD1 | 1 hits |
| 8 | IRF7 | 1 hits |
| 9 | LGALS9 | 1 hits |
| 10 | MX2 | 1 hits |
| 11 | NGFR | 1 hits |
| 12 | TRAFD1 | 1 hits |
| 13 | ZBP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21866101 | Combined with the results of previous studies of GP structure and function, our findings support a model of EboV infection in which cleavage of the GP1 subunit by endosomal cathepsin proteases removes heavily glycosylated domains to expose the amino-terminal domain, which is a ligand for NPC1 and regulates membrane fusion by the GP2 subunit. |
| 2 | 25010690 | We recently developed a systems biological approach to vaccine safety evaluation where identification of specific biomarkers in a rat pre-clinical study evaluated the safety of vaccines for pandemic H5N1 influenza including Irf7, Lgals9, Lgalsbp3, Cxcl11, Timp1, Tap2, Psmb9, Psme1, Tapbp, C2, Csf1, Mx2, Zbp1, Ifrd1, Trafd1, Cxcl9, β2m, Npc1, Ngfr and Ifi47. |
| 3 | 25010690 | Despite a slight decrease in body weight caused by HAv from manufacturer B that was not statistically significant, our results suggest that HAv from manufacturer B is significantly different than the other HAvs tested with regard to Lgals3bp, Tapbp, Lgals9, Irf7 and C2 gene expression in rat lungs. |
| 4 | 25855742 | Interaction between TIM-1 and NPC1 Is Important for Cellular Entry of Ebola Virus. |