# |
PMID |
Sentence |
1 |
1862103
|
Sequences of the principal neutralizing determinant (PND) of the external envelope protein, gp120, from 245 isolates of human immunodeficiency virus type 1 are analyzed.
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2 |
1925584
|
A titer for homologous viral neutralization activity (greater than 1:19,683) was observed after a 3.5-year immunization period with an octameric, branching peptide representing the principal neutralizing determinant (PND) of the human immunodeficiency virus-1IIIB envelope protein.
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3 |
7537750
|
This deleted gag gene allowed in a second time the insertion of a synthetic oligonucleotide cassette encoding the North American/European consensus PND precisely in place of the p24 epitope.
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4 |
8873394
|
The relative positions of the epitopes indicated that E9[V3], E14[C3] and E15[V5] correspond to the previously defined principal neutralizing determinant (PND) located in the V3 loop, the CD4 binding site and gp120 "immunodominant" region, respectively.
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5 |
9178085
|
NMR study of the peptide present in the principal neutralizing determinant (PND) of HIV-1 envelope glycoprotein gp120.
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6 |
12034093
|
A synthetic peptide immunogen designated the multiple epitope immunogen (MEI), based on the principle neutralizing domain (PND) of the third variable region (V3) of the HIV-1 subtype C surface envelope protein was prepared by combining two different modes of synthesis [Vaccine 12 (8) (1994) 736; AIDS Res.
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7 |
26075398
|
Hypertrophy (increased BNP and ANP mRNA) and fibrosis (increased collagen) of the heart were extensively present in chronically-infected WT and GPxtg mice and notably decreased after therapeutic vaccination.
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