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Gene Information

Gene symbol: OTUB1

Gene name: OTU domain, ubiquitin aldehyde binding 1

HGNC ID: 23077

Synonyms: FLJ20113, FLJ40710

Related Genes

#	Gene Symbol	Number of hits
1	NFKB1	1 hits
2	RPS27A	1 hits

Related Sentences

#	PMID	Sentence
1	20504922	In this study, we demonstrated that the PRRSV nsp2 OTU domain antagonizes the type I interferon induction by interfering with the NF-kappaB signaling pathway.
2	20504922	Further analysis revealed that the nsp2 OTU domain possesses ubiquitin-deconjugating activity.
3	20504922	This domain has the ability to inhibit NF-kappaB activation by interfering with the polyubiquitination process of IkappaBalpha, which subsequently prevents IkappaBalpha degradation.
4	20504922	The OTU domain mutants were examined to determine whether mutations in the nsp2 OTU domain region altered virus ability to inhibit NF-kappaB activation.
5	20504922	In this study, we demonstrated that the PRRSV nsp2 OTU domain antagonizes the type I interferon induction by interfering with the NF-kappaB signaling pathway.
6	20504922	Further analysis revealed that the nsp2 OTU domain possesses ubiquitin-deconjugating activity.
7	20504922	This domain has the ability to inhibit NF-kappaB activation by interfering with the polyubiquitination process of IkappaBalpha, which subsequently prevents IkappaBalpha degradation.
8	20504922	The OTU domain mutants were examined to determine whether mutations in the nsp2 OTU domain region altered virus ability to inhibit NF-kappaB activation.
9	20504922	In this study, we demonstrated that the PRRSV nsp2 OTU domain antagonizes the type I interferon induction by interfering with the NF-kappaB signaling pathway.
10	20504922	Further analysis revealed that the nsp2 OTU domain possesses ubiquitin-deconjugating activity.
11	20504922	This domain has the ability to inhibit NF-kappaB activation by interfering with the polyubiquitination process of IkappaBalpha, which subsequently prevents IkappaBalpha degradation.
12	20504922	The OTU domain mutants were examined to determine whether mutations in the nsp2 OTU domain region altered virus ability to inhibit NF-kappaB activation.
13	23401522	PLP2 binds ubiquitin using a zinc finger that is uniquely integrated into an exceptionally compact OTU-domain fold that represents a new subclass of zinc-dependent OTU DUBs.