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Gene Information

Gene symbol: PA2G4

Gene name: proliferation-associated 2G4, 38kDa

HGNC ID: 8550

Related Genes

# Gene Symbol Number of hits
1 HSPD1 1 hits

Related Sentences

# PMID Sentence
1 12683337 The single deletion of IFN-gamma or TNF alpha resulted in a severe lesion of multiple necrosis without granuloma, and cytokine mRNA level other than knocked out cytokine was normal, suggesting that IFN-gamma and TNF alpha are principally important cytokines.
2 12683337 In knockout mice for IL-12 or IL-18, necrotic lesion was not induced after infection and the pathological change was not so significant as in IFN-gamma/TNF alpha knockout mice.
3 12683337 By using IL-12, IL-18 knockout mice or double knockout mice, it was shown that IL-12 exhibits more important role than IL-18 in the protection.
4 12683337 In most of the clinical cases of tuberculosis, the production of IL-12, IL-18 and IFN-gamma is increased, however, the group of relatively lower cytokine production did not respond well to the treatment.
5 12683337 As immunizing antigens, a-Ag, ESAT-6, HSP65, 38kD-lipoprotein and so on have been employed.