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Gene Information
Gene symbol: PA2G4
Gene name: proliferation-associated 2G4, 38kDa
HGNC ID: 8550
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
12683337
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The single deletion of IFN-gamma or TNF alpha resulted in a severe lesion of multiple necrosis without granuloma, and cytokine mRNA level other than knocked out cytokine was normal, suggesting that IFN-gamma and TNF alpha are principally important cytokines.
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2 |
12683337
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In knockout mice for IL-12 or IL-18, necrotic lesion was not induced after infection and the pathological change was not so significant as in IFN-gamma/TNF alpha knockout mice.
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3 |
12683337
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By using IL-12, IL-18 knockout mice or double knockout mice, it was shown that IL-12 exhibits more important role than IL-18 in the protection.
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4 |
12683337
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In most of the clinical cases of tuberculosis, the production of IL-12, IL-18 and IFN-gamma is increased, however, the group of relatively lower cytokine production did not respond well to the treatment.
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5 |
12683337
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As immunizing antigens, a-Ag, ESAT-6, HSP65, 38kD-lipoprotein and so on have been employed.
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