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Gene Information
Gene symbol: PDGFRA
Gene name: platelet-derived growth factor receptor, alpha polypeptide
HGNC ID: 8803
Synonyms: CD140a, PDGFR2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AFP | 1 hits |
| 2 | EGFR | 1 hits |
| 3 | FGFR1 | 1 hits |
| 4 | KDR | 1 hits |
| 5 | PDGFB | 1 hits |
| 6 | PDGFRB | 1 hits |
| 7 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10458736 | Lower surface expression of AFP was observed when the TM of human platelet-derived growth factor receptor or the human asialoglycoprotein receptor H1 subunit were employed. |
| 2 | 10458736 | Introduction of the hinge-CH2-CH3 region of human IgG (gamma1 domain) between AFP and TM allowed efficient formation of disulfide-linked dimers. |
| 3 | 15728459 | The antiangiogenic drugs included (Z)-3-[4-(dimethylamino)benzylidenyl]indolin-2-one (a platelet-derived growth factor receptor beta and a fibroblast growth factor receptor 1 kinase inhibitor) and oxindole (a vascular endothelial growth factor receptor 2 kinase inhibitor). |
| 4 | 15767405 | To develop an antiprion vaccine, a retroviral display system presenting either the full-length mouse PrP (PrP209) or the C-terminal 111 amino acids (PrP111) fused to the transmembrane domain of the platelet-derived growth factor receptor was established. |
| 5 | 17050049 | Therefore we evaluated the strategy of targeting the tumor stroma with a novel DNA vaccine encoding murine platelet derived growth factor receptor-beta (mPDGFRbeta). |
| 6 | 19344189 | Standard treatments and current development of new therapies for malignant gliomas are reviewed, focusing specifically on growth factors and their receptors (e.g. epidermal growth factor receptor, vascular endothelial growth factor receptor, and platelet-derived growth factor receptor), as well as the intracellular effector molecules that are downstream of these growth factors (e.g. |
| 7 | 19344189 | Ras/Raf/mitogen-activated protein kinase, phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin, and protein kinase C). |
| 8 | 22236016 | Dysregulation of platelet-derived growth factor receptor (PDGFR) may play a role in feline injection-site sarcoma (ISS) cell growth and viability. |
| 9 | 23575987 | The mutant EGFR may also transactivate other cell surface molecules, such as additional members of the EGFR family and the platelet-derived growth factor receptor, which ignite signaling cascades that synergize with the EGFR-initiated cascade. |
| 10 | 25050066 | CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration. |
| 11 | 25050066 | The platelet-derived growth factor receptors (PDGFRs) and their ligands play critical roles in the regulation of many cancer cell processes, including cell survival and cell motility. |