|
Gene Information
Gene symbol: PDXP
Gene name: pyridoxal (pyridoxine, vitamin B6) phosphatase
HGNC ID: 30259
Synonyms: dJ37E16.5, FLJ32703
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
14613519
|
BACKGROUND: Allergic subjects produce relatively low amounts of IFN-gamma, a pleiotropic Th-1 cytokine that downregulates Th2-associated airway inflammation and hyperresponsiveness (AHR), the hallmarks of allergic asthma.
|
2 |
14613519
|
Adenovirus-mediated IFN-gamma gene transfer reduces AHR, Th2 cytokine levels and lung inflammation in mice, but its use would be limited by the frequency of gene delivery required; therefore, we tested chitosan/IFN-gamma pDNA nanoparticles (CIN) for in situ production of IFN-gamma and its in vivo effects.
|
3 |
14613519
|
Production of IFN-gamma is increased after CIN treatment while the Th2-cytokines, IL-4 and IL-5, and OVA-specific serum IgE are reduced compared to control mice.
|
4 |
14613519
|
Experiments performed on STAT4-defective mice do not show reduction in AHR with CIN treatment, thus implicating STAT4 signaling in the mechanism of CIN action.
|
5 |
16972742
|
The cervicovaginal citology is still the most accurate diagnosis method to detect SIL or CIN and invasive cancer in early stages, it is discussed the periodicity and group of women to whom the method must point.
|
|