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Gene Information

Gene symbol: PDXP

Gene name: pyridoxal (pyridoxine, vitamin B6) phosphatase

HGNC ID: 30259

Synonyms: dJ37E16.5, FLJ32703

Related Genes

# Gene Symbol Number of hits
1 AHR 1 hits
2 SILV 1 hits
3 SOCS6 1 hits

Related Sentences

# PMID Sentence
1 14613519 BACKGROUND: Allergic subjects produce relatively low amounts of IFN-gamma, a pleiotropic Th-1 cytokine that downregulates Th2-associated airway inflammation and hyperresponsiveness (AHR), the hallmarks of allergic asthma.
2 14613519 Adenovirus-mediated IFN-gamma gene transfer reduces AHR, Th2 cytokine levels and lung inflammation in mice, but its use would be limited by the frequency of gene delivery required; therefore, we tested chitosan/IFN-gamma pDNA nanoparticles (CIN) for in situ production of IFN-gamma and its in vivo effects.
3 14613519 Production of IFN-gamma is increased after CIN treatment while the Th2-cytokines, IL-4 and IL-5, and OVA-specific serum IgE are reduced compared to control mice.
4 14613519 Experiments performed on STAT4-defective mice do not show reduction in AHR with CIN treatment, thus implicating STAT4 signaling in the mechanism of CIN action.
5 16972742 The cervicovaginal citology is still the most accurate diagnosis method to detect SIL or CIN and invasive cancer in early stages, it is discussed the periodicity and group of women to whom the method must point.